1. Metastasis

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    2. Annexin A2 could enhance multidrug resistance by regulating NF-κB signaling pathway in pediatric neuroblastoma.

      ... expression of ANXA2 was closely associated with advanced stage, greater number of chemotherapy cycles, tumor metastasis and poor prognosis. Following knockdown of ANXA2 in NB cell line SK-N-BE(2) using shRNA, we demonst...
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  2. Quotes about Metastasis

    1. It would be very interesting to investigate whether these already existing drugs are beneficial for breast cancer patients. It may be possible to turn these traitors of the immune system back towards the good side and prevent their ability to promote breast cancer metastasis.
      In How immune cells facilitate the spread of breast cancer
    2. This underscores the importance of MET in the final stages of a cancer cell's metastasis, when it establishes a new malignant colony.
      In A switch to dampen malignancy
    3. While we have learned a great deal about the drivers of EMT in recent years, much less is known about the inducer of the reverse process, MET, which is equally important to both healthy development and cancer metastasis.
      In A switch to dampen malignancy