1. GvHD

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    1. Mentioned In 21 Articles

    2. Reduction of myeloid-derived suppressor cells reinforces the anti-solid tumor effect of recipient leukocyte infusion in murine neuroblastoma-bearing allogeneic bone marrow chimeras.

      ...fusion, the RLI anti-tumor effect-elicited by host-versus-graft lymphohematopoietic reactivity-does not cause GvHD; however, the tumor growth-inhibitory effect is incomplete, because overall survival is not prolonged. He...
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      Mentions: Bone Marrow GvHD
    3. Low-Dose Treatment with Interleukin-2 Across Multiple Studies Shows Benefits in Chronic Graft-Versus-Host Disease

      Low-Dose Treatment with Interleukin-2 Across Multiple Studies Shows Benefits in Chronic Graft-Versus-Host Disease
      ...teroid refractory chronic GVHD, “including in those with inadequate responses to IL-2 alone.” Because chronic GVHD is such a big problem in stem cell transplants, a variety of experimental treatments have been tried. In ...
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      Mentions: Treatment GvHD
    4. Immunotherapy Drug for Rheumatoid Arthritis Nearly Eliminates Severe Acute Graft-Versus-Host Disease after Hematopoietic Stem Cell Transplant

      ...iving hematopoietic stem cell transplants. Abatacept, when added to the standard drug regimen used to prevent GvHD, reduced the occurrence of acute, grade III-IV GvHD from 32 to 3 percent in pediatric and adult patients ...
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    5. Diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in pediatric patients: a new classification from the European society for blood and marrow transplantation

      ...f conditions increasingly designated as transplant-related, systemic endothelial diseases, that include acute GvHD, engraftment syndrome and transplant-associated microangiopathy (TAM). SOS/VOD is an unpredictable and po...
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    6. Incorporation of high-dose (131) I-metaiodobenzylguanidine treatment into killer immunoglobulin-like receptor/HLA-ligand mismatched haploidentical stem cell transplantation for children with neuroblastoma who failed tandem autologous stem cell transplanta

      ... disease (GVHD; grade I in five and grade III in one), and four of six evaluable patients experienced chronic GVHD (two mild and two severe). Four patients died from tumor progression, one died from sepsis without progre...
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      Mentions: Treatment MIBG GvHD
    7. Single-donor granulocyte transfusions for improving the outcome of high-risk pediatric patients with known bacterial and fungal infections undergoing stem cell transplantation: a 10-year single-center experience.

      ...cositis and a very low incidence (7%) of acute GvHD grade 3-4. Single-donor GTs afford protection to children undergoing SCT at additional risk of infection and may reduce the overall incidence of severe GvHD. ...
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    8. International, multi-center standardization of acute graft-versus-host disease clinical data collection: a report from the MAGIC consortium.

      ...upon by independent reviewers. The lack of standardized approaches to handle common sources of discrepancy in GVHD grading likely contributes to why promising GVHD treatments reported from single centers have failed to s...
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    9. Long-term morbidity and mortality in children with chronic graft-versus-host disease classified by National Institutes of Health consensus criteria after allogeneic hematopoietic stem cell transplantation.

      We report the long-term morbidity and mortality among 105 pediatric patients who developed chronic graft-versus-host disease (cGVHD) after allogeneic hematopoietic stem cell transplantation (HSCT).
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    10. 1-15 of 21 1 2 »
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  2. Quotes about GvHD

    1. We demonstrate for the first time that low-dose IL-2 is safe in children with advanced, steroid refractory chronic GVHD and results in a high clinical response rate.
      In Low-dose treatment with Il2 across studies shows benefits in chronic graft-versus host
    2. We demonstrate for the first time that low-dose IL-2 is safe in children with advanced, steroid refractory chronic GVHD and results in a high clinical response rate.
      In Low-Dose Treatment with Interleukin-2 Across Multiple Studies Shows Benefits in Chronic Graft-Versus-Host Disease
    3. In all my years, I've never seen a combination as successful at controlling GVHD as this.
      In Promising Drug Combination Silences the Rage of Graft-Versus-Host Disease