1. GvHD

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    1. Mentioned In 14 Articles

    2. Incorporation of high-dose (131) I-metaiodobenzylguanidine treatment into killer immunoglobulin-like receptor/HLA-ligand mismatched haploidentical stem cell transplantation for children with neuroblastoma who failed tandem autologous stem cell transplanta

      ... disease (GVHD; grade I in five and grade III in one), and four of six evaluable patients experienced chronic GVHD (two mild and two severe). Four patients died from tumor progression, one died from sepsis without progre...
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      Mentions: Treatment MIBG GvHD
    3. Single-donor granulocyte transfusions for improving the outcome of high-risk pediatric patients with known bacterial and fungal infections undergoing stem cell transplantation: a 10-year single-center experience.

      ...cositis and a very low incidence (7%) of acute GvHD grade 3-4. Single-donor GTs afford protection to children undergoing SCT at additional risk of infection and may reduce the overall incidence of severe GvHD. ...
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    4. International, multi-center standardization of acute graft-versus-host disease clinical data collection: a report from the MAGIC consortium.

      ...upon by independent reviewers. The lack of standardized approaches to handle common sources of discrepancy in GVHD grading likely contributes to why promising GVHD treatments reported from single centers have failed to s...
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    5. Long-term morbidity and mortality in children with chronic graft-versus-host disease classified by National Institutes of Health consensus criteria after allogeneic hematopoietic stem cell transplantation.

      We report the long-term morbidity and mortality among 105 pediatric patients who developed chronic graft-versus-host disease (cGVHD) after allogeneic hematopoietic stem cell transplantation (HSCT).
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    6. Feasibility of HLA-haploidentical hematopoietic stem cell transplantation with post-transplantation cyclophosphamide for advanced pediatric malignancies.

      ...stem cell transplantation (n = 2). The incidence of severe acute GHVD was 25.0% and that of extensive chronic GVHD 0.0% after evaluable BMT. CR was achieved in 6/15 and partial response in 4/15 as the best response. Fina...
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    7. Rabbit Virus Improves Bone Marrow Transplants, Kills Some Cancer Cells

      Rabbit Virus Improves Bone Marrow Transplants, Kills Some Cancer Cells
      Newswise University of Florida Health researchers have discovered that a rabbit virus can deliver a one-two punch, killing some kinds of cancer cells while eliminating a common and dangerous complication of bone marrow transplants. For patients with blood cancers such as leukemia and multiple myeloma, a bone marrow transplant can be both curative and perilous.
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    8. T-cell depleted allogeneic hematopoietic cell transplants as a platform for adoptive therapy with leukemia selective or virus-specific T-cells.

      ...ia-reactive donor T-cells can be adoptively transferred and can induce remissions of leukemia relapse without GVHD. Similarly, virus-specific T-cells generated from the transplant donor or an HLA partially matched third ...
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    9. CNCF 2010 ~ Allogeneic (donor) stem cell transplant for neuroblastoma

      ...d to GVHD, the patient did enter a CR sustained for at least 4 years. In a more recent report, development of GVHD correlated temporally with disease response in a patient who had undergone a reduced-intensity allogeneic...
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  2. Quotes about GvHD

    1. We then tested this concept in patients with chronic GVHD in collaboration with members of our bone marrow transplant team, hematologist-oncologists Carol Richman and Joseph Tuscano.
      In Anti-Cancer Drug Effective Against Common Stem Cell Transplant Complication
    2. In all my years, I've never seen a combination as successful at controlling GVHD as this.
      In Promising Drug Combination Silences the Rage of Graft-Versus-Host Disease
    3. The GVHD took a greater toll than cancer or the transplant itself.
      In Promising Drug Combination Silences the Rage of Graft-Versus-Host Disease