1. Chemotherapy

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    1. Mentioned In 109 Articles

    2. Nivolumab in Combination With Metronomic Chemotherapy in Paediatrics Refractory / Relapsing Solid Tumors or Lymphoma

      Nivolumab in Combination With Metronomic Chemotherapy in Paediatrics Refractory / Relapsing Solid Tumors or Lymphoma
      Conditions :   Childhood Solid Tumor;   Childhood Lymphoma Interventions :   Drug: Vinblastine;   Drug: Cyclophosphamide;   Drug: Capecitabine;   Drug: Nivolumab Sponsors :   Centre Oscar Lambret;   Anticancer Fund, Belgium;   Bristol-Myers Squibb Not yet recruiting
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    3. Feasibility of High-dose Iodine-131-metaiodobenzylguanidine Therapy for High-risk Neuroblastoma Preceding Myeloablative Chemotherapy and Hematopoietic Stem Cell Transplantation: a Study Protocol.

      ... study is to evaluate the safety and efficacy of 131I-MIBG radiotherapy combined with myeloablative high-dose chemotherapy and hematopoietic stem cell transplantation. Patients with high-risk neuroblastoma will be enroll...
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      Mentions: MIBG Chemotherapy
    4. Long-term outcomes of the GPOH NB97 trial for children with high-risk neuroblastoma comparing high-dose chemotherapy with autologous stem cell transplantation and oral chemotherapy as consolidation.

      ...h high-risk neuroblastoma comparing high-dose chemotherapy with autologous stem cell transplantation and oral chemotherapy as consolidation. Br J Cancer. 2018 Jul 11;: Authors: Berthold F, Ernst A, Hero B, Klingeb...
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      Mentions: GPOH Chemotherapy
    5. Suppression of RRM2 inhibits cell proliferation, causes cell cycle arrest and promotes the apoptosis of human neuroblastoma cells and in human neuroblastoma RRM2 is suppressed following chemotherapy.

      ... III and IV tumors in the chemotherapy subgroup, compared with levels noted in tumors in the preoperative non‑chemotherapy subgroup. RRM2 siRNA significantly inhibited cell viability in the SH‑5Y5Y cells, induced cell ar...
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      Mentions: Chemotherapy
    6. Targeted Doxorubicin-Loaded Bacterially Derived Nano-Cells for the Treatment of Neuroblastoma

      Targeted Doxorubicin-Loaded Bacterially Derived Nano-Cells for the Treatment of Neuroblastoma
      ...r pediatric cancers offers promise to improve treatment efficacy and reduce toxicity associated with systemic chemotherapy. The EnGeneIC Dream Vector (EDVTM) is a nanocell, which can package chemotherapeutic drugs and ta...
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    7. Dehydroeffusol inhibits viability and epithelial-mesenchymal transition through the Hedgehog and Akt/mTOR signaling pathways in neuroblastoma cells.

      ...Neuroblastoma (NB) is the most predominant extracranial solid tumor of infancy in the world. However, current chemotherapy has limited efficacy for more advanced stages of NB due to acquired chemoresistance or acute toxi...
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      Mentions: Chemotherapy
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  2. Quotes about Chemotherapy

    1. For those diagnosed with solid cancer tumours the compounds have the potential to prevent the disease from spreading into the lymphatic system and might be given alongside chemotherapy, Four drugs were used in zebrafish and then taken and tried in mammalian models/mice.
      In Anti-cancer lymphatic drugs show potential
    2. New drugs are desperately needed for children with ALL who relapse after their chemotherapy. Our findings show that selumetinib could be very effective at treating a substantial proportion of these children. The drug actually targets faults specific to the leukaemia cells, limiting damage to healthy cells and debilitating side-effects.
      In Potential new drug for childhood leukaemia
    3. In most cases, cancer patients who receive chemotherapy lose their fast-growing normal cells, including hair, nails and lining of the gut.
      In MSU Scientists Find Way to Boost Healthy Cells During Chemo