1. Bone Marrow

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    1. Mentioned In 67 Articles

    2. Prospective investigation of applicability and the prognostic significance of bone marrow involvement in patients with neuroblastoma detected by quantitative reverse transcription PCR.

      ...horikov EV, Tsaur GA, Popov AM, Zaychikov AN, Tuponogov SN, Saveliev LI, Tytgat GAM, Fechina LG Detection of bone marrow (BM) involvement in patients with neuroblastoma is crucial for staging and defining prognosis. Fur...
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      Mentions: Bone Marrow PHOX2B
    3. Prospective investigation of applicability and the prognostic significance of bone marrow involvement in patients with neuroblastoma detected by quantitative reverse transcription PCR

      Expression of PHOX2B , TH , ELAVL4 , and B4GALNT1 (GD2‐synthase) was analyzed by quantitative polymerase chain reaction in neuroblastoma cell lines, control BM samples, and in BM samples from patients. The threshold level of expression for each gene was established through receiver operator characteristic analysis and used to determine the diagnostic test performance. The prognostic significance of BM involvement was assessed by survival rates calculations.
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      Mentions: Bone Marrow PHOX2B
    4. miRNA expression profile of bone marrow resident cells from children with neuroblastoma is not significantly different from that of healthy children.

      ...or metastatic disease. MiR-221 over-expression was unlikely derived from neuroblastoma primary tumors or from bone marrow-infiltrating metastatic cells, since neuroblastoma cells expressed lower or similar amount of miR-...
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      Mentions: Bone Marrow
    5. High-dose Carboplatin/Etoposide/Melphalan increases risk of thrombotic microangiopathy and organ injury after autologous stem cell transplantation in patients with neuroblastoma.

      ...icroangiopathy and organ injury after autologous stem cell transplantation in patients with neuroblastoma. Bone Marrow Transplant. 2018 Apr 19;: Authors: Jodele S, Dandoy CE, Myers K, Wallace G, Lane A, Teusink-Cr...
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      Mentions: Bone Marrow
    6. Event‐free survival of infants and toddlers enrolled in the HR‐NBL‐1/SIOPEN trial is associated with the level of neuroblastoma mRNAs at diagnosis

      ...nd PHOX2B in bone marrow and of PHOX2B in peripheral blood during the first year of follow‐up. High levels of bone marrow TH and PHOX2B and of peripheral blood PHOX2B at diagnosis allow early identification of a group of...
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    7. Reduction of myeloid-derived suppressor cells reinforces the anti-solid tumor effect of recipient leukocyte infusion in murine neuroblastoma-bearing allogeneic bone marrow chimeras.

      ...ith GvHD. Adoptive recipient leukocyte infusion (RLI) was shown to enhance anti-tumor responses of allogeneic bone marrow transplantation in murine neuroblastoma (Neuro2A)-bearing chimeras. In contrast to the clinically ...
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      Mentions: Bone Marrow GvHD
    8. Change in liver, spleen and bone marrow magnetic resonance imaging signal intensity over time in children with solid abdominal tumors.

      ... with neuroblastoma exhibited significantly lower hepatic (P=0.03) signal intensity ratios. Liver, spleen and bone marrow T2-weighted MRI signal intensity ratios change over time in some pediatric patients with solid abd...
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      Mentions: Imaging Bone Marrow
    9. Prognostic value of metabolic indices and bone marrow uptake pattern on preoperative 18F-FDG PET/CT in pediatric patients with neuroblastoma.

      ...liable prognostic information for neuroblastoma pediatric patients, and patients with high MTV, TLG and focal bone marrow (unifocal and multifocal) uptake on PET/CT may have inferior outcomes during subsequent treatment....
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    10. Diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in pediatric patients: a new classification from the European society for blood and marrow transplantation

      ...in pediatric patients: a new classification from the European society for blood and marrow transplantation Bone Marrow Transplantation 53, 138 (February 2018). doi:10.1038/bmt.2017.161 Major advances ...
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    11. Expression of Five Neuroblastoma Genes in Bone Marrow or Blood of Patients with Relapsed/Refractory Neuroblastoma Provides a New Biomarker for Disease and Prognosis.

      ...PFS in relapsed/refractory NB." We determined if quantifying neuroblastoma (NB)-associated mRNAs (NB-mRNA) in bone marrow (BM) and blood improves assessment of disease and prediction of disease progression in patients wi...
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    12. MYCN amplification predicts poor prognosis based on interphase fluorescence in situ hybridization analysis of bone marrow cells in bone marrow metastases of neuroblastoma.

      ...edicts poor prognosis based on interphase fluorescence in situ hybridization analysis of bone marrow cells in bone marrow metastases of neuroblastoma. Cancer Cell Int. 2017;17:43 Authors: Yue ZX, Huang C, Gao C, X...
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      Mentions: MYCN Bone Marrow LDH
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  2. Quotes about Bone Marrow

    1. As a transplant physician, it's beyond heartbreaking to witness a patient develop severe acute graft-versus-host disease after having their leukemia cured through bone marrow transplant.
      In Immunotherapy Drug for Rheumatoid Arthritis Nearly Eliminates Severe Acute Graft-Versus-Host Disease after Hematopoietic Stem Cell Transplant
    2. She's had six rounds of chemo. She's had a bone marrow transplant. She's had 20 rounds of radiation.
      In Genomic screening helps doctors target girl's cancer
    3. We've known for decades that cancer has harnessed the immune system to keep pumping out large numbers of mature and immature myeloid cells from the bone marrow.
      In Cells identified that enhance tumor growth and suppress anti-cancer immune attack