Identification of a Novel Aminotetralin Class of HDAC6 and HDAC8 Selective Inhibitors.
J Med Chem. 2014 Sep 19;
Authors: Tang G, Wong JC, Zhang W, Wang Z, Zhang N, Peng Z, Zhang Z, Rong Y, Li S, Zhang M, Yu L, Feng T, Zhang X, Wu X, Wu JZ, Chen L
Abstract Herein we report the identification of a novel class of HDAC6 and HDAC8 selective inhibitors through a unique chemistry and phenotypic screening strategy.