1. Articles from ncbi.nlm.nih.gov

  2. 1537-1560 of 1681 « 1 2 ... 62 63 64 65 66 67 68 69 70 »
    1. Identification of a Novel Aminotetralin Class of HDAC6 and HDAC8 Selective Inhibitors.

      Identification of a Novel Aminotetralin Class of HDAC6 and HDAC8 Selective Inhibitors.

      J Med Chem. 2014 Sep 19;

      Authors: Tang G, Wong JC, Zhang W, Wang Z, Zhang N, Peng Z, Zhang Z, Rong Y, Li S, Zhang M, Yu L, Feng T, Zhang X, Wu X, Wu JZ, Chen L

      Abstract Herein we report the identification of a novel class of HDAC6 and HDAC8 selective inhibitors through a unique chemistry and phenotypic screening strategy.

      Read Full Article
    2. Involvement of store-operated Ca2+ entry in activation of AMP-activated protein kinase and stimulation of glucose uptake by M3 muscarinic acetylcholine receptors in human neuroblastoma cells.

      Involvement of store-operated Ca(2+) entry in activation of AMP-activated protein kinase and stimulation of glucose uptake by M3 muscarinic acetylcholine receptors in human neuroblastoma cells.

      Biochim Biophys Acta. 2014 Sep 18;

      Authors: Olianas MC, Dedoni S, Onali P

      Read Full Article
    3. Outcomes After Radiation Therapy to Metastatic Sites in Patients With Stage 4 Neuroblastoma.

      Outcomes After Radiation Therapy to Metastatic Sites in Patients With Stage 4 Neuroblastoma.

      J Pediatr Hematol Oncol. 2014 Sep 18;

      Authors: Kandula S, Prabhu RS, Nanda R, Switchenko JM, Cash T, Qayed M, Katzenstein H, Esiashvili N

      Abstract In patients with high-risk metastatic neuroblastoma, the benefit of radiation therapy (RT) to metastatic sites as part of primary treatment has not been fully investigated.

      Read Full Article
    4. Synthesis of New Quinoxalines Containing an Oxirane Ring by the TDAE Strategy and in Vitro Evaluation in Neuroblastoma Cell Lines.

      Synthesis of New Quinoxalines Containing an Oxirane Ring by the TDAE Strategy and in Vitro Evaluation in Neuroblastoma Cell Lines.

      Molecules. 2014;19(9):14987-98

      Authors: Montana M, Correard F, Khoumeri O, Esteve MA, Terme T, Vanelle P

      Abstract Neuroblastoma is an aggressive pediatric malignancy with significant chemotherapeutic resistance.

      Read Full Article
    5. MYCN gene amplification in patients with neuroblastic tumors.

      MYCN gene amplification in patients with neuroblastic tumors.

      Cell Mol Biol (Noisy-le-grand). 2014;60(3):23-8

      Authors: Estiar MA, Fazilaty H, Aslanabadi S, Seifi M, Varghaei P, Rezamand A

      Abstract Although neuroblastic tumors are the most prevalent solid tumors, little is known about the genetic basis underlying their progression. The prognostic role for the MYCN gene in neuroblastic tumors is irrefutable.

      Read Full Article
      Mentions: MYCN
    6. Revised risk estimation and treatment stratification of low- and intermediate-risk neuroblastoma patients by integrating clinical and molecular prognostic markers.

      Revised risk estimation and treatment stratification of low- and intermediate-risk neuroblastoma patients by integrating clinical and molecular prognostic markers.

      Clin Cancer Res. 2014 Sep 17;

      Authors: Oberthuer A, Juraeva D, Hero B, Volland R, Carolina S, Schmidt R, Faldum A, Kahlert Y, Engesser A, Asgharzadeh S, Seeger RC, Ohira M, Nakagawara A, Scaruffi P, Tonini GP, Janoueix-Lerosey I, Delattre O, Schleiermacher G, Vandesompele J, Speleman F, Noguera R, Piqueras M, Benard J, Valent A, Avigad S, Yaniv I, Grundy RG, Ortmann M, Shao C, Schwab M, Eils R, Simon T, Theissen J, Berthold F, Westermann F, Brors B, Fischer M ...

      Read Full Article
      Mentions: GPOH Diagnostics
    7. Cardiotoxicity and cardioprotection in childhood cancer.

      Cardiotoxicity and cardioprotection in childhood cancer.

      Acta Haematol. 2014;132(3-4):391-9

      Authors: Lipshultz SE, Sambatakos P, Maguire M, Karnik R, Ross SW, Franco VI, Miller TL

      Abstract Children diagnosed with cancer are now living longer as a result of advances in treatment. However, some commonly used anticancer drugs, although effective in curing cancer, can also cause adverse late effects.

      Read Full Article
      Mentions: Treatment
    8. Molecular rationale for the use of PI3K/AKT/mTOR pathway inhibitors in combination with crizotinib in ALK-mutated neuroblastoma.

      Molecular rationale for the use of PI3K/AKT/mTOR pathway inhibitors in combination with crizotinib in ALK-mutated neuroblastoma.

      Oncotarget. 2014 Aug 19;

      Authors: Moore NF, Azarova AM, Bhatnagar N, Ross KN, Drake LE, Frumm S, Liu QS, Christie AL, Sanda T, Chesler L, Kung AL, Gray NS, Stegmaier K, George RE

      Read Full Article
      Mentions: ALK
    9. Lessons from the Fourth Metronomic and Anti-angiogenic Therapy Meeting, 24-25 June 2014, Milan.

      Lessons from the Fourth Metronomic and Anti-angiogenic Therapy Meeting, 24-25 June 2014, Milan.

      Ecancermedicalscience. 2014;8:463

      Authors: Bouche G, André N, Banavali S, Berthold F, Berruti A, Bocci G, Brandi G, Cavallaro U, Cinieri S, Colleoni M, Curigliano G, Desidero TD, Eniu A, Fazio N, Kerbel R, Hutchinson L, Ledzewicz U, Munzone E, Pasquier E, Graciela Scharovsky O, Shaked Y, StÄ›rba J, Villalba M, Bertolini F

      Read Full Article
    10. Pediatric Intensive Care Outcomes: Development of New Morbidities During Pediatric Critical Care.

      Pediatric Intensive Care Outcomes: Development of New Morbidities During Pediatric Critical Care.

      Pediatr Crit Care Med. 2014 Sep 15;

      Authors: Pollack MM, Holubkov R, Funai T, Clark A, Berger JT, Meert K, Newth CJ, Shanley T, Moler F, Carcillo J, Berg RA, Dalton H, Wessel DL, Harrison RE, Doctor A, Dean JM, Jenkins TL, for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network

      Read Full Article
    11. Viral infection of implanted meningeal tumors induces antitumor memory T-cells to travel to the brain and eliminate established tumors.

      Viral infection of implanted meningeal tumors induces antitumor memory T-cells to travel to the brain and eliminate established tumors.

      Neuro Oncol. 2014 Sep 14;

      Authors: Gao Y, Whitaker-Dowling P, Barmada MA, Basse PH, Bergman I

      Abstract BACKGROUND: Leptomeningeal metastases occur in 2%-5% of patients with breast cancer and have an exceptionally poor prognosis. The blood-brain and blood-meningeal barriers severely inhibit successful chemotherapy.

      Read Full Article
      Mentions: T-Cells
    12. Neuroblastoma Patient-Derived Orthotopic Xenografts Retain Metastatic Patterns and Geno- and Phenotypes of Patient Tumours.

      Neuroblastoma Patient-Derived Orthotopic Xenografts Retain Metastatic Patterns and Geno- and Phenotypes of Patient Tumours.

      Int J Cancer. 2014 Sep 15;

      Authors: Braekeveldt N, Wigerup C, Gisselsson D, Mohlin S, Merselius M, Beckman S, Jonson T, Börjesson A, Backman T, Tadeo I, Berbegall AP, Ora I, Navarro S, Noguera R, Påhlman S, Bexell D

      Read Full Article
    13. BMP2-Smad-Mediated SH-SY5Y Neuroblastoma Cell Proliferation and Neurite Outgrowth Are Regulated Through Dynamin-Dependent Endocytosis.

      BMP2-Smad-Mediated SH-SY5Y Neuroblastoma Cell Proliferation and Neurite Outgrowth Are Regulated Through Dynamin-Dependent Endocytosis.

      Mol Neurobiol. 2014 Sep 14;

      Authors: Yang X, Lv S, Li D, Lv W, Fan K, Sheng L, Shi R, Zhang J, Feng M, Xu Z

      Abstract Smad signalling plays an important role in the neurobiology, which can be induced by bone morphogenetic protein 2 (BMP2) and be regulated by endocytosis.

      Read Full Article
    14. Olfactory neuroblastoma behavior inside and outside the olfactory cleft.

      Olfactory neuroblastoma behavior inside and outside the olfactory cleft.

      Surg Radiol Anat. 2014 Sep 14;

      Authors: Jankowski R, Russel A, Gallet P, Henrot P, Vignaud JM, Nguyen DT

      Abstract PURPOSE: Olfactory neuroblastoma (ONB) is a rare malignant tumor of the nose. The currently available evidence links this disease with cells of the olfactory epithelium. The detailed description of tumor site and its extension is the key of treatment.

      Read Full Article
    15. The Tell-Tale Heart: Molecular and Cellular Responses to Childhood Anthracycline Exposure.

      The Tell-Tale Heart: Molecular and Cellular Responses to Childhood Anthracycline Exposure.

      Am J Physiol Heart Circ Physiol. 2014 Sep 12;

      Authors: Lindsey ML, Lange RA, Parsons H, Andrews T, Aune GJ

      Abstract Since the modern era of cancer chemotherapy that began in the mid 1940's, survival rates for children afflicted with cancer have steadily improved from 10% to current rates that approach 80%.

      Read Full Article
    16. Grief reactions and impact of patient death on pediatric oncologists.

      Grief reactions and impact of patient death on pediatric oncologists.

      Pediatr Blood Cancer. 2014 Sep 11;

      Authors: Granek L, Bartels U, Scheinemann K, Labrecque M, Barrera M

      Abstract BACKGROUND: To examine pediatric oncologists' grief reactions to patient death, and the impact patient death has on their personal and professional lives. PROCEDURE: The grounded theory method was used. Data was collected between March 2012 and July 2012 at two academic centres in Canada.

      Read Full Article
    17. Importance of blood cultures from peripheral veins in pediatric patients with cancer and a central venous line.

      Importance of blood cultures from peripheral veins in pediatric patients with cancer and a central venous line.

      Pediatr Blood Cancer. 2014 Sep 11;

      Authors: Handrup MM, Møller JK, Rutkjaer C, Schrøder H

      Abstract BACKGROUND: When an infection is suspected in a child with cancer and a central venous line (CVL), cultures are often only obtained from the CVL and not from a peripheral vein (PV).

      Read Full Article
    18. Mitochondrial ferritin, a new target for inhibiting neuronal tumor cell proliferation.

      Mitochondrial ferritin, a new target for inhibiting neuronal tumor cell proliferation.

      Cell Mol Life Sci. 2014 Sep 12;

      Authors: Shi ZH, Shi FF, Wang YQ, Sheftel AD, Nie G, Zhao YS, You LH, Gou YJ, Duan XL, Zhao BL, Xu HM, Li CY, Chang YZ

      Abstract Mitochondrial ferritin (FtMt) has a significant effect on the regulation of cytosolic and mitochondrial iron levels.

      Read Full Article
    19. Childhood cancer survival rates in two South African units.

      Childhood cancer survival rates in two South African units.

      S Afr Med J. 2014 Jul;104(7):501-4

      Authors: Stones DK, De Bruin GP, Esterhuizen TM, Stefan DC

      Abstract Introduction. Childhood cancer is relatively rare, but there is a very good chance of cure. While overall survival rates of >70% are reported from developed countries, survival is much less likely in developing countries and unknown in many countries in Africa.Objective.

      Read Full Article
    20. Aggressive primary olfactory neuroblastoma of the sphenoclival region: A case report and literature review.

      Aggressive primary olfactory neuroblastoma of the sphenoclival region: A case report and literature review.

      Laryngoscope. 2014 Sep 12;

      Authors: Purohit B, Winder T, Maggio EM, Kollias SS

      Abstract Olfactory neuroblastoma (ONB) is an uncommon malignant tumor of neural crest origin, which commonly arises in the superior nasal cavity. Ectopic origin of an ONB is exceedingly rare.

      Read Full Article
    21. Pharmacokinetics of the chimeric anti-GD2 antibody, ch14.18, in children with high-risk neuroblastoma.

      Pharmacokinetics of the chimeric anti-GD2 antibody, ch14.18, in children with high-risk neuroblastoma.

      Cancer Chemother Pharmacol. 2014 Sep 12;

      Authors: Desai AV, Fox E, Smith LM, Lim AP, Maris JM, Balis FM

      Abstract PURPOSE: Ch14.18 improves survival in children with high-risk neuroblastoma but is associated with substantial toxicity.

      Read Full Article
      Mentions: Antibody
    1537-1560 of 1681 « 1 2 ... 62 63 64 65 66 67 68 69 70 »
  1. Categories

    1. Research:

      Cancer Cell, Case Report, Cells and Stem Cells, Clinical Research, Conferences, Disease Classification, Drug, Drug Delivery, Drug Resistance, Epigenetics and Epigenomics, General, Genetics, Genomics, Guidelines, Immune Therapy, Induction, Long Term Effects, Low / Intermediate Risk, Nanotechnology, Olfactory Neuroblastoma, Onco-Fertility, Oncogenesis, Other Cancers, Personalized Medicine, Pharma, Pre-Clinical, Prognostics, PubMed, Review, Small Molecules, Surgery, Survivorship, Trials, Tumor Biology, Virotherapy
    2. Business:

      Funding, IP, Pharma
    3. Non-Profit:

      Advocacy, Charity, Events, Foundation, Funding, Human Interest
    4. Press Release:

      Announcement, News, Pharma
    5. General:

      Adolescent and Young Adults, Bioethics, Blog, Burden of Treatment, Children & Families, Diagnosis and Detection, Drug Development, Epidemiology, Imaging, Incidence, Information, News, Overview of the Disease, Pain Control, Palliative Care, Psychosocial, Regulation, Side-Effects, Social, Supportive Care, Treatment
    6. Media:

      Audio, Blogs, Video