1. 1-23 of 23
    1. Genetic analysis for certain childhood brain tumors soon a standard-of-care?

      Genetic analysis for certain childhood brain tumors soon a standard-of-care?

      An international team of researchers from the Hopp Children’s Cancer Center at the NCT Heidelberg (KiTZ), the European Molecular Biology Laboratory (EMBL) and the German Cancer Consortium (DKTK) together with colleagues at the St. Jude Children’s Research Hospital in Memphis and the Hospital for Sick Children in Toronto has summarized hereditary gene defects which can […]

      The post Genetic analysis for certain childhood brain tumors soon a standard-of-care? appeared first on Healthcanal.com.

      Read Full Article
    2. Combination therapy in neuroblastoma: It`s all about the mix

      The combination of two cell division inhibitors causes malignant nervous system tumors to die off, as scientists from the “Hopp Children’s Cancer Center at the NCT Heidelberg” (KiTZ) have shown in experimental studies.The combination strategy could be the key to new targeted therapies against this aggressive type of tumor. The Hopp Children’s Cancer Center at […]

      The post Combination therapy in neuroblastoma: It`s all about the mix appeared first on Healthcanal.com.

      Read Full Article
      Mentions: ALK
    3. A molecular map of childhood cancers

      A molecular map of childhood cancers

      Researchers led by Professor Stefan Pfister from the “Hopp Children’s Cancer Center at the NCT Heidelberg” (KiTZ) have been able to draw an extremely detailed molecular map of childhood cancers. In close collaboration with the German Cancer Consortium (DKTK) and the Society for Pediatric Oncology and Hematology (GPOH), they screened almost 1,000 tumor samples from […]

      The post A molecular map of childhood cancers appeared first on Healthcanal.com.

      Read Full Article
      Mentions: GPOH Genetics
    4. Study Identifies Patients Who Benefit Most From Dinutuximab-based Immunotherapy

      Using data from a randomized phase III clinical trial of neuroblastoma patients (treated with or without immunotherapy) performed by the Children’s Oncology Group, researchers from the University of Wisconsin School of Medicine and Public Health found that a subset of patients, identified by the presence of a certain set of genes, were more likely to benefit from […]

      The post Study Identifies Patients Who Benefit Most From Dinutuximab-based Immunotherapy appeared first on Healthcanal.com.

      Read Full Article
      Mentions: Immunotherapy
    5. A new molecular target to improve neuroblastoma treatment

      The collaborative work, in which UPV/EHU and Achucarro Center researchers have participated, has served to identify some genetic mutations that will help to improve the treatment of this disease The annual mortality rate in childhood cancer of the sympathetic nervous system, or neuroblastoma, is 10 per million between the ages of 0 and 4. The […]

      The post A new molecular target to improve neuroblastoma treatment appeared first on Healthcanal.com.

      Read Full Article
      Mentions: Treatment
    6. Simple test predicts childhood cancer relapse

      Simple test predicts childhood cancer relapse

      Researchers at Brunel University London and University College London have pinpointed a protein marker, which when absent, shows neuroblastoma is almost certain to recur. It means children with low-risk neuroblastoma, who don’t have the biomarker called PML, can be reclassified as at high risk of relapse and have chemotherapy earlier. A cheap simple test could accurately predict the recurrence of a childhood cancer.

      Read Full Article
    7. New Research from Memorial Sloan Kettering Highlights Fertility Concerns of Young Adult and Adolescent Cancer Survivors

      New Rochelle, NY —Nearly half of young adult survivors of adolescent cancers--more young men than women--report uncertainty about their fertility, according to the results of a new study. While females were more likely to describe feeling distressed and overwhelmed and tended to worry more about pregnancy-related health risks and cancer recurrence, both sexes had concerns about genetic risk factors and how infertility might impact their future lives, as described in the study published in Journal of Adolescent and Young Adult Oncology (JAYAO), a multidisciplinary peer-reviewed publication from Mary Ann Liebert, Inc., publishers. The article is available free on the JAYAO ...

      Read Full Article
    8. Researchers discover cancer markers may be visible early during human development

      BLACKSBURG, Va. – Researchers at the Virginia Bioinformatics Institute have uncovered a link between the genomes of cells originating in the neural crest and development of tumors — a discovery that could lead to new ways to diagnose and treat cancer. The new finding, recently published in Oncotarget, resolves why some cancer types share genomic and clinical features.

      Read Full Article
    9. Children's National Finds Neuroblastoma Tumor Cure in Mice Studies

      A method to cure neuroblastoma tumors in mice has been discovered by Children's National researchers, opening the door for future clinical studies for a therapeutic patient-specific vaccine to cure one of the most common childhood cancers. Anthony Sandler, MD, Senior Vice President, the Joseph E. Robert, Jr., Center for Surgical Care, led the study that was published in PLOS ONE.

      Read Full Article
    10. Insights into a signaling process that enhances the effectiveness of cancer immunotherapy

      Insights into a signaling process that enhances the effectiveness of cancer immunotherapy

      "The NCI researchers found that some CAR T cells undergo early T cell exhaustion, a functional state that limits their effectiveness in fighting cancer. The researchers also found that changing the types of costimulatory signals that are included in the CAR can improve the function of CAR T cells by preventing exhaustion."

      Read Full Article
    11. A second chance for children with cancer

      A second chance for children with cancer

      Today most cases of childhood cancer can be cured. However, in about 20 percent of cases children suffer a recurrence of the cancer following therapy and they ultimately succumb to the disease. With a new project called INFORM*, scientists from the German Cancer Research Center (DKFZ) and the German Consortium for Translational Cancer Research (DKTK) aim to provide these children with a second avenue toward cures.

      Read Full Article
      Mentions: GPOH Relapse
    12. Promising Steps Toward Combination Treatment of Deadly Pediatric Cancer

      Promising Steps Toward Combination Treatment of Deadly Pediatric Cancer

      Anaplastic lymphoma kinase (ALK) activity has been identified as one of the basic processes in neuroblastoma, which accounts for approximately 15% of all fatal cases of pediatric cancer. A study published in Science Signaling by researchers at Sahlgrenska Academy points the way to targeting ALK in treatment of the deadly disease.

      Read Full Article
      Mentions: ALK MYCN
    1-23 of 23
  1. Categories

    1. Research:

      Cancer Cell, Case Report, Cells and Stem Cells, Clinical Research, Conferences, Disease Classification, Drug, Drug Delivery, Drug Resistance, Epigenetics and Epigenomics, General, Genetics, Genomics, Guidelines, Immune Therapy, Induction, Long Term Effects, Low / Intermediate Risk, Nanotechnology, Olfactory Neuroblastoma, Onco-Fertility, Oncogenesis, Other Cancers, Personalized Medicine, Pharma, Pre-Clinical, Prognostics, PubMed, Review, Small Molecules, Surgery, Survivorship, Trials, Tumor Biology, Virotherapy
    2. Business:

      Funding, IP, Pharma
    3. Non-Profit:

      Advocacy, Charity, Events, Foundation, Funding, Human Interest
    4. Press Release:

      Announcement, News, Pharma
    5. General:

      Adolescent and Young Adults, Bioethics, Blog, Burden of Treatment, Children & Families, Diagnosis and Detection, Drug Development, Epidemiology, Imaging, Incidence, Information, News, Overview of the Disease, Pain Control, Palliative Care, Psychosocial, Regulation, Side-Effects, Social, Supportive Care, Treatment
    6. Media:

      Audio, Blogs, Video