1. Articles in category: Adolescent and Young Adults

    1-24 of 28 1 2 »
    1. Health-related quality of life and psychological distress in young adult survivors of childhood cancer and their association with treatment, education, and demographic factors.

      Health-related quality of life and psychological distress in young adult survivors of childhood cancer and their association with treatment, education, and demographic factors.

      Qual Life Res. 2017 Oct 31;:

      Authors: Halvorsen JF, Sund AM, Zeltzer L, Ådnanes M, Jensberg H, Eikemo TA, Lund B, Hjemdal O, Reinfjell T

      Read Full Article
      Mentions: Treatment
    2. Nutritional Characteristics of the Diets of Child and Adolescent Cancer Survivors.

      Nutritional Characteristics of the Diets of Child and Adolescent Cancer Survivors.

      J Adolesc Young Adult Oncol. 2017 Oct 12;:

      Authors: Teixeira JFC, Maia-Lemos PDS, Pisani LP

      Abstract PURPOSE: Diseases associated with prior treatment, such as obesity, have been described in cancer survivors. Recent studies have shown that current estimates of overweight do not differ from that in the general population, suggesting the influence of environmental factors, such as dietary intake.

      Read Full Article
      Mentions: Treatment
    3. Investigational drugs in phase II clinical trials for the treatment of neuroblastoma.

      Investigational drugs in phase II clinical trials for the treatment of neuroblastoma.

      Expert Opin Investig Drugs. 2017 Sep 14;:

      Authors: Amoroso L, Haupt R, Garaventa A, Ponzoni M

      Abstract INTRODUCTION: Neuroblastoma (NB) is an embryonal tumor originating from undifferentiated neural crest cell, highly heterogeneous ranging from spontaneous regression to progression despite multimodal treatments.

      Read Full Article
      Mentions: Treatment
    4. Study shows incisionless surgery with MR-HIFU effective in destroying painful bone tumors

      Study shows incisionless surgery with MR-HIFU effective in destroying painful bone tumors

      Doctors from the Sheikh Zayed Institute for Pediatric Surgical Innovation at Children's National Health System have completed a clinical trial that demonstrates how osteoid osteoma, a benign but painful bone tumor that commonly occurs in children and young adults, can be safely and successfully treated using an incisionless surgery method called magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU).

      Read Full Article
      Mentions: Surgery
    5. A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies

      Conditions :   Relapsed or Refractory Malignancies;   Relapsed or Refractory Acute Lymphoblastic Leukemia (ALL);   Relapsed or Refractory Acute Myeloid Leukemia (AML);   Relapsed or Refractory Non-Hodgkin Lymphoma (NHL);   Relapsed or Refractory Neuroblastoma;   Relapsed or Refractory Tumors That Expresses B Cell Lymphoma 2 (BCL-2) Interventions :   Drug: venetoclax;   Drug: chemotherapy Sponsors :   AbbVie;   Genentech/Roche Not yet recruiting - verified July 2017

      Read Full Article
      Mentions: Refractory
    6. Seattle Children's Opens CD22 CAR T-Cell Immunotherapy Trial for Children and Young Adults Whose Leukemia Escapes CD19 CAR T-Cell Therapy

      Seattle Children's Opens CD22 CAR T-Cell Immunotherapy Trial for Children and Young Adults Whose Leukemia Escapes CD19 CAR T-Cell Therapy

      After seeing promising results in phase 1 of the Pediatric Leukemia Adoptive Therapy (PLAT-02) trial with 93 percent of patients with relapsed or refractory acute lymphoblastic leukemia (ALL) achieving complete initial remission, researchers at Seattle Children's are continuing their quest to improve the experimental therapy and reduce the rate of relapse, which is about 50 percent.

      Read Full Article
    7. Seattle Children's opens CD22 CAR T-cell immunotherapy trial for children and young adults

      Seattle Children's opens CD22 CAR T-cell immunotherapy trial for children and young adults

      ( Seattle Children's ) After seeing promising results in phase 1 of the Pediatric Leukemia Adoptive Therapy (PLAT-02) trial with 93 percent of patients with relapsed or refractory acute lymphoblastic leukemia (ALL) achieving complete initial remission, researchers at Seattle Children's are continuing their quest to improve the experimental therapy and reduce the rate of relapse, which is about 50 percent.

      Read Full Article
    8. ICR scientists awarded £1.5m precision medicine funding for targeted, less toxic childhood cancer treatments

      ICR scientists awarded £1.5m precision medicine funding for targeted, less toxic childhood cancer treatments

      Scientists from The Institute of Cancer Research, London, have been awarded £1.5 million by the charity Children with Cancer UK to advance precision medicine in the UK and improve cancer treatment for children and young adults.

      Read Full Article
      Mentions: Treatment
    9. Recommendations for gonadotoxicity surveillance in male childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCareSurFup Consort

      Recommendations for gonadotoxicity surveillance in male childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCareSurFup Consortium.

      Lancet Oncol. 2017 Feb;18(2):e75-e90

      Read Full Article
    10. Two investigational antitumor agents work better together against MPNST and neuroblastoma

      Two investigational antitumor agents work better together against MPNST and neuroblastoma

      Two investigational agents, Aurora A kinase inhibitor (alisertib) and HSV1716, a virus derived from HSV-1 and attenuated by the deletion of RL1, have shown some antitumor efficacy in early clinical trials as monotherapies. A new study published last week in Oncotarget, however, demonstrates that the combined usage of the agents results in significantly increased antitumor efficacy in models of malignant peripheral nerve sheath tumor (MPNST) and neuroblastoma.

      Read Full Article
    11. Skeletal outcome in long-term survivors of childhood high-risk neuroblastoma treated with high-dose therapy and autologous stem cell rescue.

      Skeletal outcome in long-term survivors of childhood high-risk neuroblastoma treated with high-dose therapy and autologous stem cell rescue.

      Bone Marrow Transplant. 2017 Jan 09;:

      Authors: Utriainen P, Vatanen A, Toiviainen-Salo S, Saarinen-Pihkala U, Mäkitie O, Jahnukainen K

      Read Full Article
      Mentions: Bone Marrow
    12. Transition and transfer of childhood cancer survivors to adult care: A national survey of pediatric oncologists

      "Of 347 respondents, 50% are male, median years in practice 10 (range 5–22), 37% practice in freestanding children's hospitals. Almost all care for survivors up to age 21 years (96%), 42% care for survivors over age 25 years, and only 16% over age 30 years. While 66% of oncologists reported providing transition education to their patients, very few (8%) reported using standardized transition assessments. The most frequent barriers to transfer were perceived attachment to provider (91%), lack of adult providers with cancer survivor expertise (86%), patient's cognitive delay (81%), or unstable social situation (80%). Oncologists who continue ...

      Read Full Article
      Mentions: COG
    13. A Qualitative Inquiry of Childhood and Adolescent Cancer Survivors' Perspectives of Independence.

      "Among the 21 survivors who reported that cancer affected their independence, themes included challenges and motivators to independence following cancer. Challenges to independence included overprotection by parents, financial dependence, problems in healthcare decision-making, and emotional dependence. Motivators included self-confidence, desire for independence, parental support, and inadequate family support."

      Read Full Article
    14. "Being a good patient" during times of illness as defined by adolescent patients with cancer.

      "Being a good patient" during times of illness as defined by adolescent patients with cancer.

      Cancer. 2016 May 3;

      Authors: Weaver MS, Baker JN, Gattuso JS, Gibson DV, Hinds PS

      Abstract BACKGROUND: Adolescents with cancer cite the opinions of others and expected impact on others as formative for their care preferences and decisions.

      Read Full Article
    15. Fertility after childhood cancer varies by sex, chemotherapy dose

      "The majority of female survivors of childhood cancers retained the ability to become pregnant in adulthood, according to study results published in The Lancet Oncology.  However, male cancer survivors — especially those treated with greater doses of alkylating drugs and cisplatin chemotherapy — appeared less likely to remain fertile, results showed."

      Read Full Article
      Mentions: Chemotherapy
    16. Identifying Barriers Among Childhood Cancer Survivors Transitioning to Adult Health Care.

      Identifying Barriers Among Childhood Cancer Survivors Transitioning to Adult Health Care.

      J Pediatr Oncol Nurs. 2016 Mar 11;

      Authors: Quillen J, Bradley H, Calamaro C

      Abstract The aim of this study was to identify and describe barriers of young adult childhood cancer survivors transitioning to adult health care within 5 years of leaving a pediatric oncology practice.

      Read Full Article
    17. Support from healthcare services during transition to adulthood - Experiences of young adult survivors of pediatric cancer.

      Support from healthcare services during transition to adulthood - Experiences of young adult survivors of pediatric cancer.

      Eur J Oncol Nurs. 2016 Apr;21:105-12

      Authors: Svedberg P, Einberg EL, Wärnestål P, Stigmar J, Castor A, Enskär K, Nygren JM

      Abstract PURPOSE: Improved survival rates of pediatric cancer have drawn attention on how to best facilitate long-term follow up and transition from pediatric to adult care.

      Read Full Article
    18. Clinical application of genomic profiling to find druggable targets for adolescent and young adult (AYA) cancer patients with metastasis.

      Clinical application of genomic profiling to find druggable targets for adolescent and young adult (AYA) cancer patients with metastasis.

      BMC Cancer. 2016;16(1):170

      Authors: Cha S, Lee J, Shin JY, Kim JY, Sim SH, Keam B, Kim TM, Kim DW, Heo DS, Lee SH, Kim JI

      Read Full Article
      Mentions: Metastasis
    19. Fulfilling the Vision of Youth-Friendly Cancer Care: A Study Protocol.

      "Eligible patients were 15-25 years old and 6-24 months from a cancer diagnosis, and a nominated carer. Stage 1 consisted of in-depth, semi-structured interviews. Qualitative analysis identified the major domains affected by cancer. Stage 2 was the development of a survey tool for AYA and parents to measure these domains, compiled from validated instruments of: psychological distress; post-traumatic growth; quality of life; social support; quality of services, information, and needs; physical, psychological, and social needs; self-management; and experience of care, as well as questions covering additional domains (e.g., fertility preservation). Stage 3 was a national survey of AYAs and ...

      Read Full Article
    20. New Research from Memorial Sloan Kettering Highlights Fertility Concerns of Young Adult and Adolescent Cancer Survivors

      New Rochelle, NY —Nearly half of young adult survivors of adolescent cancers--more young men than women--report uncertainty about their fertility, according to the results of a new study. While females were more likely to describe feeling distressed and overwhelmed and tended to worry more about pregnancy-related health risks and cancer recurrence, both sexes had concerns about genetic risk factors and how infertility might impact their future lives, as described in the study published in Journal of Adolescent and Young Adult Oncology (JAYAO), a multidisciplinary peer-reviewed publication from Mary Ann Liebert, Inc., publishers. The article is available free on the JAYAO ...

      Read Full Article
    1-24 of 28 1 2 »
  1. Categories

    1. Research:

      Cancer Cell, Case Report, Cells and Stem Cells, Clinical Research, Conferences, Disease Classification, Drug, Drug Delivery, Drug Resistance, Epigenetics and Epigenomics, General, Genetics, Genomics, Guidelines, Immune Therapy, Induction, Long Term Effects, Low / Intermediate Risk, Nanotechnology, Olfactory Neuroblastoma, Onco-Fertility, Oncogenesis, Other Cancers, Personalized Medicine, Pharma, Pre-Clinical, Prognostics, PubMed, Review, Small Molecules, Surgery, Survivorship, Trials, Tumor Biology, Virotherapy
    2. Business:

      Funding, IP, Pharma
    3. Non-Profit:

      Advocacy, Charity, Events, Foundation, Funding, Human Interest
    4. Press Release:

      Announcement, News, Pharma
    5. General:

      Adolescent and Young Adults, Bioethics, Blog, Burden of Treatment, Children & Families, Diagnosis and Detection, Drug Development, Epidemiology, Imaging, Incidence, Information, News, Overview of the Disease, Pain Control, Palliative Care, Psychosocial, Regulation, Side-Effects, Social, Supportive Care, Treatment
    6. Media:

      Audio, Blogs, Video
  2. Popular Articles

  3. General Informations in the News

    1. (1 articles) Treatment