1. Articles in category: Adolescent and Young Adults

    1-20 of 20
    1. ICR scientists awarded £1.5m precision medicine funding for targeted, less toxic childhood cancer treatments

      ICR scientists awarded £1.5m precision medicine funding for targeted, less toxic childhood cancer treatments

      Scientists from The Institute of Cancer Research, London, have been awarded £1.5 million by the charity Children with Cancer UK to advance precision medicine in the UK and improve cancer treatment for children and young adults.

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      Mentions: Treatment
    2. Recommendations for gonadotoxicity surveillance in male childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCareSurFup Consort

      Recommendations for gonadotoxicity surveillance in male childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCareSurFup Consortium.

      Lancet Oncol. 2017 Feb;18(2):e75-e90

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    3. Two investigational antitumor agents work better together against MPNST and neuroblastoma

      Two investigational antitumor agents work better together against MPNST and neuroblastoma

      Two investigational agents, Aurora A kinase inhibitor (alisertib) and HSV1716, a virus derived from HSV-1 and attenuated by the deletion of RL1, have shown some antitumor efficacy in early clinical trials as monotherapies. A new study published last week in Oncotarget, however, demonstrates that the combined usage of the agents results in significantly increased antitumor efficacy in models of malignant peripheral nerve sheath tumor (MPNST) and neuroblastoma.

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    4. Skeletal outcome in long-term survivors of childhood high-risk neuroblastoma treated with high-dose therapy and autologous stem cell rescue.

      Skeletal outcome in long-term survivors of childhood high-risk neuroblastoma treated with high-dose therapy and autologous stem cell rescue.

      Bone Marrow Transplant. 2017 Jan 09;:

      Authors: Utriainen P, Vatanen A, Toiviainen-Salo S, Saarinen-Pihkala U, Mäkitie O, Jahnukainen K

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      Mentions: Bone Marrow
    5. Transition and transfer of childhood cancer survivors to adult care: A national survey of pediatric oncologists

      "Of 347 respondents, 50% are male, median years in practice 10 (range 5–22), 37% practice in freestanding children's hospitals. Almost all care for survivors up to age 21 years (96%), 42% care for survivors over age 25 years, and only 16% over age 30 years. While 66% of oncologists reported providing transition education to their patients, very few (8%) reported using standardized transition assessments. The most frequent barriers to transfer were perceived attachment to provider (91%), lack of adult providers with cancer survivor expertise (86%), patient's cognitive delay (81%), or unstable social situation (80%). Oncologists who continue ...

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      Mentions: COG
    6. A Qualitative Inquiry of Childhood and Adolescent Cancer Survivors' Perspectives of Independence.

      "Among the 21 survivors who reported that cancer affected their independence, themes included challenges and motivators to independence following cancer. Challenges to independence included overprotection by parents, financial dependence, problems in healthcare decision-making, and emotional dependence. Motivators included self-confidence, desire for independence, parental support, and inadequate family support."

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    7. "Being a good patient" during times of illness as defined by adolescent patients with cancer.

      "Being a good patient" during times of illness as defined by adolescent patients with cancer.

      Cancer. 2016 May 3;

      Authors: Weaver MS, Baker JN, Gattuso JS, Gibson DV, Hinds PS

      Abstract BACKGROUND: Adolescents with cancer cite the opinions of others and expected impact on others as formative for their care preferences and decisions.

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    8. Fertility after childhood cancer varies by sex, chemotherapy dose

      "The majority of female survivors of childhood cancers retained the ability to become pregnant in adulthood, according to study results published in The Lancet Oncology.  However, male cancer survivors — especially those treated with greater doses of alkylating drugs and cisplatin chemotherapy — appeared less likely to remain fertile, results showed."

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      Mentions: Chemotherapy
    9. Identifying Barriers Among Childhood Cancer Survivors Transitioning to Adult Health Care.

      Identifying Barriers Among Childhood Cancer Survivors Transitioning to Adult Health Care.

      J Pediatr Oncol Nurs. 2016 Mar 11;

      Authors: Quillen J, Bradley H, Calamaro C

      Abstract The aim of this study was to identify and describe barriers of young adult childhood cancer survivors transitioning to adult health care within 5 years of leaving a pediatric oncology practice.

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    10. Support from healthcare services during transition to adulthood - Experiences of young adult survivors of pediatric cancer.

      Support from healthcare services during transition to adulthood - Experiences of young adult survivors of pediatric cancer.

      Eur J Oncol Nurs. 2016 Apr;21:105-12

      Authors: Svedberg P, Einberg EL, Wärnestål P, Stigmar J, Castor A, Enskär K, Nygren JM

      Abstract PURPOSE: Improved survival rates of pediatric cancer have drawn attention on how to best facilitate long-term follow up and transition from pediatric to adult care.

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    11. Clinical application of genomic profiling to find druggable targets for adolescent and young adult (AYA) cancer patients with metastasis.

      Clinical application of genomic profiling to find druggable targets for adolescent and young adult (AYA) cancer patients with metastasis.

      BMC Cancer. 2016;16(1):170

      Authors: Cha S, Lee J, Shin JY, Kim JY, Sim SH, Keam B, Kim TM, Kim DW, Heo DS, Lee SH, Kim JI

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      Mentions: Metastasis
    12. Fulfilling the Vision of Youth-Friendly Cancer Care: A Study Protocol.

      "Eligible patients were 15-25 years old and 6-24 months from a cancer diagnosis, and a nominated carer. Stage 1 consisted of in-depth, semi-structured interviews. Qualitative analysis identified the major domains affected by cancer. Stage 2 was the development of a survey tool for AYA and parents to measure these domains, compiled from validated instruments of: psychological distress; post-traumatic growth; quality of life; social support; quality of services, information, and needs; physical, psychological, and social needs; self-management; and experience of care, as well as questions covering additional domains (e.g., fertility preservation). Stage 3 was a national survey of AYAs and ...

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    13. New Research from Memorial Sloan Kettering Highlights Fertility Concerns of Young Adult and Adolescent Cancer Survivors

      New Rochelle, NY —Nearly half of young adult survivors of adolescent cancers--more young men than women--report uncertainty about their fertility, according to the results of a new study. While females were more likely to describe feeling distressed and overwhelmed and tended to worry more about pregnancy-related health risks and cancer recurrence, both sexes had concerns about genetic risk factors and how infertility might impact their future lives, as described in the study published in Journal of Adolescent and Young Adult Oncology (JAYAO), a multidisciplinary peer-reviewed publication from Mary Ann Liebert, Inc., publishers. The article is available free on the JAYAO ...

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    14. Pilot Study of Massage to Improve Sleep and Fatigue in Hospitalized Adolescents With Cancer

      Adolescents with cancer experience many troubling symptoms, including sleep disruptions that can affect mood and quality of life. Massage is a safe and popular intervention that has demonstrated efficacy in pediatric and adult patients with cancer. This study aimed to assess the feasibility of conducting a massage intervention to help with sleep in hospitalized adolescent oncology patients.

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    15. First Tool to Assess Impact of Co-illnesses in Young Cancer Patients

      First Tool to Assess Impact of Co-illnesses in Young Cancer Patients

      "Little or no improvement in cancer survival rates has been achieved in this age group for decades. These patients too frequently fall between pediatric and adult oncology. The study, funded by the National Cancer Institute (NCI), is part of the Adolescent & Young Adult Health Outcomes & Patient Experience (AYA HOPE) Study designed to address the disparities.  Previous studies show that having comorbidities adversely affect treatment, quality of life, service needs, and survivorship care in adult cancer survivors. Co-illnesses may increase the toxicity of specific treatments, increase hospitalizations, create difficulties with treatment, and lead to higher health care costs and death."

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    16. Distinct health behavior and psychosocial profiles of young adult survivors of childhood cancers: a mixed methods study.

      "Assessing health behavior profiles, rather than individual health behaviors, is informative in characterizing young adult cancer survivors and targeting survivorship care.  Young adult cancer survivors demonstrate distinct health behavior profiles and are differentially impacted by the experience of cancer. Healthcare providers should be consistently intervening to ensure that survivors understand their specific health risks."

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    17. Understanding the healthcare experiences of teenaged cancer patients and survivors.

      "Likes and dislikes were conceptualized in terms of four key themes as follows: (1) staff at the treatment centre; (2) the cancer care they received; (3) the treatment centre itself; and (4) social activities. The most common suggestions for the perfect cancer centre included having access to better entertainment, more social opportunities to interact with peers, and a more comfortable environment for themselves and their families."

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    1-20 of 20
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