1. Articles in category: Other Cancers

    1-24 of 71 1 2 3 »
    1. New potential treatment for aggressive types of childhood cancer

      New potential treatment for aggressive types of childhood cancer

      A combination of substances that impacts chemical modifications in the DNA of tumours and triggers the tumours to differentiate into harmless nerve cells could represent a new method of treating aggressive forms of neuroblastoma. The new method has been proposed by researchers at Karolinska Institutet, after studies using mice showed that the combination treatment resulted in a significant suppression in tumour growth.

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      Mentions: Treatment
    2. Metabolic syndrome induced by anticancer treatment in childhood cancer survivors.

      Metabolic syndrome induced by anticancer treatment in childhood cancer survivors.

      Ann Pediatr Endocrinol Metab. 2017 Jun;22(2):82-89

      Authors: Chueh HW, Yoo JH

      Abstract The number of childhood cancer survivors is increasing as survival rates improve. However, complications after treatment have not received much attention, particularly metabolic syndrome.

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      Mentions: Treatment
    3. Expansion of cancer germline antigen-specific cytotoxic T lymphocytes for immunotherapy.

      Expansion of cancer germline antigen-specific cytotoxic T lymphocytes for immunotherapy.

      Tumour Biol. 2017 Jul;39(7):1010428317701309

      Authors: Krishnadas DK, Wang Y, Sundaram K, Bai F, Lucas KG

      Abstract The cancer germline antigens MAGE-A1, MAGE-A3, and NY-ESO-1 can be used to target relapsed or therapy-resistant malignant solid tumors, and previous studies have demonstrated that these antigens can be epigenetically upregulated on the surface of tumor cells following exposure to low-dose demethylating chemotherapy agents, such as decitabine. The extent to which cancer germline antigen cytotoxic T lymphocytes can be reliably expanded from healthy donors has not been well characterized, specifically in ...

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    4. Pain in Children with Cancer: Prevalence, Characteristics, and Parent Management.

      Pain in Children with Cancer: Prevalence, Characteristics, and Parent Management.

      Clin J Pain. 2017 Jul 03;:

      Authors: Tutelman PR, Chambers CT, Stinson JN, Parker JA, Fernandez CV, Witteman HO, Nathan PC, Barwick M, Campbell F, Jibb LA, Irwin K

      Abstract OBJECTIVES: Pain is a common and distressing symptom of pediatric cancer, as reported by both children and their parents.

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    5. Bromodomain and extraterminal protein inhibitors in pediatrics: A review of the literature.

      Bromodomain and extraterminal protein inhibitors in pediatrics: A review of the literature.

      Pediatr Blood Cancer. 2017 May;64(5):

      Authors: Jiménez I, Baruchel A, Doz F, Schulte J

      Abstract The last few years have seen the identification of pharmacologic approaches to target bromodomain and extraterminal (BET) proteins for cancer treatment.

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      Mentions: Treatment
    6. Neonates with cancer and causes of death; lessons from 615 cases in the SEER databases.

      Neonates with cancer and causes of death; lessons from 615 cases in the SEER databases.

      Cancer Med. 2017 Jun 22;:

      Authors: Alfaar AS, Hassan WM, Bakry MS, Qaddoumi I

      Abstract Neonatal tumors are rare with no standard treatment approaches to these diseases, and the patients experience poor outcomes. Our aim was to determine the distribution of cancers affecting neonates and compare survival between these cancers and older children.

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      Mentions: Treatment
    7. MRI without contrast agents? Yes, with sugar!

      MRI without contrast agents? Yes, with sugar!

      ( German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) ) Scientists from the German Cancer Research Center (DKFZ), in collaboration with colleagues from Heidelberg University Hospital, have been able to visualize brain cancer using a novel MRI method. They use a simple sugar solution instead of conventional contrast agents, which can have side effects in the body.

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      Mentions: Side Effects
    8. New biomarker assay detects neuroblastoma with greater sensitivity

      New biomarker assay detects neuroblastoma with greater sensitivity

      ( Children's Hospital Los Angeles ) Investigators at The Saban Research Institute of Children's Hospital Los Angeles have developed and tested a new biomarker assay for quantifying disease and detecting the presence of neuroblastoma even when standard evaluations yield negative results for the disease.

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      Mentions: NANT MIBG
    9. New research points to potential targeted treatments of neuroblastoma tumours

      New research points to potential targeted treatments of neuroblastoma tumours

      Genetic variations appear to pre-dispose children to developing certain severe forms of neuroblastoma, according to new research by the University of Chicago Medicine.

      The findings lay the groundwork for developing more targeted treatments for...

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      Mentions: MYCN
    10. Potential for more targeted treatments of neuroblastoma tumors

      Genetic variations appear to pre-dispose children to developing certain severe forms of neuroblastoma, according to new research. The findings lay the groundwork for developing more targeted treatments for particularly deadly variations of the cancer.

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      Mentions: MYCN
    11. New research points to potential for more targeted treatments of neuroblastoma tumors

      New research points to potential for more targeted treatments of neuroblastoma tumors

      ( University of Chicago Medical Center ) Genetic variations appear to pre-dispose children to developing certain severe forms of neuroblastoma, according to new research by the University of Chicago Medicine. The findings lay the groundwork for developing more targeted treatments for particularly deadly variations of the cancer.

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      Mentions: MYCN
    12. Giving children a voice in clinical trials

      Giving children a voice in clinical trials

      ( Children's National Health System ) Children as young as 8 years old with incurable cancer can reliably characterize the impact an experimental therapy has on their symptoms and quality of life -- even at the earliest stages of drug development -- making self-reported patient outcomes a potential new clinical trial endpoint.

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    13. Results Indicate That Larotrectinib Is Effective as the First Novel Targeted Therapy to Show a Consistent Response across Multiple Tumor Types in Adult and Pediatric Patients

      Results Indicate That Larotrectinib Is Effective as the First Novel Targeted Therapy to Show a Consistent Response across Multiple Tumor Types in Adult and Pediatric Patients

      Larotrectinib (LOXO-101) has demonstrated consistent and durable antitumor activity in tropomyosin receptor kinase (TRK) fusion cancers across a wide range of patient ages and tumor types and was well tolerated by patients, according to results from three clinical trials presented today at the annual meeting of the American Society of Clinical Oncology in Chicago.

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    14. Chronic health conditions among long-term survivors of childhood cancer decrease over three decades as treatments improve

      Chronic health conditions among long-term survivors of childhood cancer decrease over three decades as treatments improve

      MEMPHIS, Tenn., June 2, 2017 /PRNewswire/ -- Changes in the treatment of pediatric cancer over recent decades have translated to a reduced risk of serious, long-term late health effects of cancer therapy. This is according to the latest analysis from the Childhood Cancer Survivor Study (CC...

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      Mentions: Treatment
    15. AACR Publishes First Set of Screening Recommendations Emerging from Childhood Cancer Predisposition Workshop

      AACR Publishes First Set of Screening Recommendations Emerging from Childhood Cancer Predisposition Workshop

      ​PHILADELPHIA — The American Association for Cancer Research (AACR) has published its first set of consensus screening recommendations for children with common cancer predisposition syndromes in Clinical Cancer Research, a journal of the AACR. These recommendations emerged from the Childhood Cancer Predisposition Workshop held by the AACR Pediatric Cancer Working Group in October 2016.

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      Mentions: Imaging
    16. A new molecular target to improve neuroblastoma treatment

      The collaborative work, in which UPV/EHU and Achucarro Center researchers have participated, has served to identify some genetic mutations that will help to improve the treatment of this disease The annual mortality rate in childhood cancer of the sympathetic nervous system, or neuroblastoma, is 10 per million between the ages of 0 and 4. The […]

      The post A new molecular target to improve neuroblastoma treatment appeared first on Healthcanal.com.

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      Mentions: Treatment
    1-24 of 71 1 2 3 »
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