1. Articles in category: Bioethics

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    1. Appeal On Refusal Of Children’s Cancer Treatment Upheld Solving Kids’ Cancer Successfully Challenges NICE Decision

      Appeal On Refusal Of Children’s Cancer Treatment Upheld Solving Kids’ Cancer Successfully Challenges NICE Decision

      "The National Institute for Health and Care Excellence (NICE) has today announced that it has upheld the appeal by Solving Kids’ Cancer against the Institute’s decision not to recommend dinutuximab for treating high-risk neuroblastoma. The decision on whether to recommend dinutuximab will now be referred back to the Appraisal Committee for reconsideration. Solving Kids’ Cancer had argued that NICE had exceeded its powers and was in breach of the UN Convention on the Rights of the Child, and that using a 10-year cure point as the basis for the drug’s effectiveness was unreasonable given the evidence before it."

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      Mentions: Treatment
    2. An Ethical Framework for Allocating Scarce Life-Saving Chemotherapy and Supportive Care Drugs for Childhood Cancer.

      "The ethical framework proposed in this Commentary is based upon multidisciplinary expert opinion, further strengthened by an independent panel of peer consultants. The two-step allocation process includes strategies to mitigate existing shortages by minimizing waste and addresses actual prioritization across and within diseases according to a modified utilitarian model that maximizes total benefit while respecting limited constraints on differential treatment of individuals. The framework provides reasoning for explicit decision-making in the face of an actual drug shortage. Moreover, it minimizes bias that might occur when individual clinicians or institutions are forced to make bedside rationing and prioritization decisions and addresses ...

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      Mentions: Chemotherapy
    3. Leading Pediatric Oncologist Group Releases Guidance for Rationing Childhood Cancer Drugs in Anticipation of Future Drug Shortages

      "Our intention with this project was to try to help the childhood cancer community manage the crisis that will occur when, not if, the next drug shortage happens," said COG Chairman Dr. Peter Adamson. "This is a problem almost exclusively impacting children in the United States and not other developed countries. The problem should be preventable, but will require the government to take additional steps to address the fundamental causes of these shortages. Until further action is taken, we are doing everything in our power to help prepare for the next shortage when pediatric oncologists may be forced into rationing ...

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      Mentions: COG Chemotherapy
    4. ASHG Issues Position Statement on Genetic Testing in Children And Adolescents

      ASHG Issues Position Statement on Genetic Testing in Children And Adolescents

      BETHESDA, MD - The American Society of Human Genetics (ASHG) Workgroup on Pediatric Genetic and Genomic Testing has issued a position statement on Points to Consider: Ethical, Legal, and Psychosocial Implications of Genetic Testing in Children and Adolescents. Published today in The American Journal of Human Genetics, the statement aims to guide approaches to genetic testing for children in the research and clinical contexts.

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