1. Articles in category: Overview of the Disease

    1-11 of 11
    1. Clinical manifestations of neuroblastoma with head and neck involvement in children.

      Clinical manifestations of neuroblastoma with head and neck involvement in children.

      Int J Pediatr Otorhinolaryngol. 2017 Jun;97:157-162

      Authors: Alvi S, Karadaghy O, Manalang M, Weatherly R

      Abstract OBJECTIVE: The purpose of our study is to review our 15-year experience with pediatric patients who have been diagnosed with neuroblastoma, and to determine their most frequent head and neck manifestations and symptoms. STUDY DESIGN: Retrospective chart review of electronic medical record.

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    2. Traditional and complementary medicine used with curative intent in childhood cancer: A systematic review.

      Traditional and complementary medicine used with curative intent in childhood cancer: A systematic review.

      Pediatr Blood Cancer. 2017 Feb 28;:

      Authors: Diorio C, Salena K, Ladas EJ, Lam CG, Afungcwhi GM, Njuguna F, Marjerrison S

      Abstract Traditional and complementary medicine (T&CM) strategies are widely utilized in pediatric oncology, with many families reporting T&CM use with the intention to cure cancer.

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    3. Traditional and complementary medicine used with curative intent in childhood cancer: A systematic review

      Traditional and complementary medicine (T&CM) strategies are widely utilized in pediatric oncology, with many families reporting T&CM use with the intention to cure cancer. Study of T&CM agents presents many challenges, as a heterogeneous group of agents and techniques are used for a variety of different purpose in many different oncologic conditions. We present a systematic review of the literature examining published reports in which T&CM agents are used with an intention of cure.

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    4. Prevalence of cardiovascular late sequelae in long-term survivors of childhood cancer: A systematic review and meta-analysis

      Cardiovascular diseases are well-known late effects of childhood cancer and research on these late effects is a highly important emerging field. We conducted a systematic review with a meta-analysis to give an overview of the current evidence and the prevalence of late cardiovascular events.

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    5. Treatment and outcome of neuroblastoma with intraspinal extension: A systematic review.

      Treatment and outcome of neuroblastoma with intraspinal extension: A systematic review.

      Pediatr Blood Cancer. 2017 Feb 02;:

      Authors: Kraal K, Blom T, van Noesel M, Kremer L, Caron H, Tytgat G, van der Pal H

      Abstract We performed a systematic review to define the long-term health problems and optimal treatment strategy for patients with neuroblastoma with intraspinal extension. Of 685 identified studies, 28 were included in this review.

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      Mentions: Treatment
    6. Neuroblastoma Treatment (PDQ®): Patient Version.

      "This PDQ cancer information summary has current information about the treatment of neuroblastoma. It is meant to inform and help patients, families, and caregivers. It does not give formal guidelines or recommendations for making decisions about health care. Editorial Boards write the PDQ cancer information summaries and keep them up to date."

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      Mentions: Treatment
    7. Neuroblastoma.

      "This article presents an overview of the key clinical features of neuroblastoma and current therapeutic approaches. It also highlights how our understanding of sympathoadrenal developmental biology, coupled with transcriptome analyses, next-generation sequencing, and genome-wide association and epigenetic studies, has illuminated critical signal transduction pathways involved in neuroblastoma tumorigenesis and identified therapeutically tractable targets for clinical development."

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    8. Neuroblastoma: Paradigm for Precision Medicine.

      "Neuroblastoma (NB) is the third most common pediatric cancer. Although NB accounts for 7% of pediatric malignancies, it is responsible for more than 10% of childhood cancer-related mortality. Prognosis and treatment are determined by clinical and biological risk factors. Estimated 5-year survival rates for patients with non-high-risk and high-risk NB are more than 90% and less than 50%, respectively. Recent clinical trials have continued to reduce therapy for patients with non-high-risk NB, including the most favorable subsets who are often followed with observation approaches. In contrast, high-risk patients are treated aggressively with chemotherapy, radiation, surgery, and myeloablative and immunotherapies."

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      Mentions: Treatment
    9. State of the art in oncology: high risk neuroblastoma, alveolar rhabdomyosarcoma, desmoplastic small round cell tumor, and POST-TEXT 3 and 4 hepatoblastoma.

      "Despite advances in the treatment of pediatric cancers during the past few decades, high-risk neuroblastoma, alveolar rhabdomyosarcoma, desmoplastic small round cell tumor, and hepatoblastomas with 3 or 4 sector involvement after chemotherapy continue to present significant challenges. This review summarizes recent research on the management of these diseases, with a special focus on the use of surgical debulking, genetic analysis, immunotherapy, and chemotherapy in improving outcomes of patients with these solid tumors."

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    10. Review Article ~ Advances in Neuroblastoma

      Review Article ~ Advances in Neuroblastoma

      June 2010 review by Dr John Maris in the New England Journal of Medicine (click on image for full-text, posted with permission at CNCFhope.org):

      You can also follow the link below to view a 24 minute webcast of an April 2010 AACR meeting presented by John Maris: “Bridging the Gap: Moving Laboratory Discoveries into Clinical Trials”.
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    1-11 of 11
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