1. Articles in category: Long Term Effects

    1-24 of 80 1 2 3 4 »
    1. Aerobic Exercise in Anthracycline-Induced Cardiotoxicity: A Systematic Review of Current Evidence and Future Directions.

      "Although effective and widely used, particularly in the pediatric population, side effects including dose-dependent association with cardiac dysfunction limits its usage. Unfortunately, there is only one US FDA-approved drug (dexrazoxane) available for the prevention and mitigation of cardiotoxicity related to anthracycline therapy. While aerobic exercise has been shown to reduce cardiovascular complications in multiple diseases, its role as a therapeutic approach to mitigate cardiovascular consequences of cancer therapy is in its infancy. This systematic review aims to summarize how aerobic exercise can help to alleviate unintended cardiotoxic side effects and identify gaps in need of further research. While published work ...

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    2. Erectile Dysfunction in Male Survivors of Childhood Cancer-A Report From the Childhood Cancer Survivor Study.

      Erectile Dysfunction in Male Survivors of Childhood Cancer-A Report From the Childhood Cancer Survivor Study.

      J Sex Med. 2016 Apr 21;

      Authors: Ritenour CW, Seidel KD, Leisenring W, Mertens AC, Wasilewski-Masker K, Shnorhavorian M, Sklar CA, Whitton JA, Stovall M, Constine LS, Armstrong GT, Robison LL, Meacham LR

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    3. Associations between Psychological Problems and Quality of Life in Pediatric Short Stature from Patients’ and Parents’ Perspectives

      by Julia Hannah Quitmann, Monika Bullinger, Rachel Sommer, Anja Christine Rohenkohl, Neuza Maria Bernardino Da Silva

      Short stature has been associated with psychosocial impairments, but whether treatments and achieved height impact on health-related quality of life (HrQoL) and psychological functioning of children/adolescents is still controversial.

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    4. Renal Cell Carcinoma Occurring in Patients With Prior Neuroblastoma: A Heterogenous Group of Neoplasms.

      Renal Cell Carcinoma Occurring in Patients With Prior Neuroblastoma: A Heterogenous Group of Neoplasms.

      Am J Surg Pathol. 2016 Mar 11;

      Authors: Falzarano SM, McKenney JK, Montironi R, Eble JN, Osunkoya AO, Guo J, Zhou S, Xiao H, Dhanasekaran SM, Shukla S, Mehra R, Magi-Galluzzi C

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    5. Children's Hospital of Michigan DMC Research Team Leads Clinical Trial to Protect the Hearts of Children Who Receive Chemotherapy

      Published in the upcoming March 10, 2016 issue of the authoritative Journal of Clinical Oncology, this new study is likely to change the standard of cardiac care during treatment of many childhood cancer patients.

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    6. Cause-Specific Long-Term Mortality in Survivors of Childhood Cancer in Switzerland: A Population Based Study.

      Cause-Specific Long-Term Mortality in Survivors of Childhood Cancer in Switzerland: A Population Based Study.

      Int J Cancer. 2016 Mar 7;

      Authors: Schindler M, Spycher BD, Ammann RA, Ansari M, Michel G, Kuehni CE, Swiss Paediatric Oncology Group (SPOG), Swiss Paediatric Oncology Group SPOG

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    7. Evaluation and Management of Hearing Loss in Survivors of Childhood and Adolescent Cancers: A Report From the Children's Oncology Group

      Hearing loss (HL) is common in childhood cancer survivors exposed to platinum chemotherapy and/or cranial radiation and can severely impact quality of life. Early detection and appropriate management can mitigate academic, speech, language, social, and psychological morbidity resulting from hearing deficits. This review is targeted as a resource for providers involved in aftercare of childhood cancers.

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    8. Neuroblastoma With Intraspinal Extension: Health Problems in Long-Term Survivors.

      Neuroblastoma With Intraspinal Extension: Health Problems in Long-Term Survivors.

      Pediatr Blood Cancer. 2016 Feb 18;

      Authors: Kraal K, Blom T, Tytgat L, van Santen H, van Noesel M, Smets A, Bramer J, Caron H, Kremer L, van der Pal H

      Abstract AIM: To evaluate the prevalence of health problems in 5-year survivors treated for neuroblastoma (NBL) with intraspinal extension.

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    9. Impaired Left Ventricular Reserve in Childhood Cancer Survivors Treated With Anthracycline Therapy

      Childhood cancer survivors show evidence of diffuse myocardial fibrosis that is related to exercise capacity. The mechanism of reduced exercise tolerance in anthracycline cardiotoxicity remains unclear. We explored the determinants of exercise intolerance by evaluating left ventricular (LV) distensibility and functional reserve.

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    10. [Exposure to CT scans in childhood and long-term cancer risk: A review of epidemiological studies].

      [Exposure to CT scans in childhood and long-term cancer risk: A review of epidemiological studies].

      Bull Cancer. 2016 Jan 15;

      Authors: Baysson H, Journy N, Roué T, Ducou-Lepointe H, Etard C, Bernier MO

      Abstract Amongst medical exams requiring ionizing radiation, computed tomography (CT) scans are used more frequently, including in children. These CT examinations are associated with absorbed doses that are much higher than those associated with conventional radiology.

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    11. Radiotherapy and subsequent thyroid cancer in German childhood cancer survivors: a nested case-control study.

      Radiotherapy and subsequent thyroid cancer in German childhood cancer survivors: a nested case-control study.

      Radiat Oncol. 2015;10(1):219

      Authors: Finke I, Scholz-Kreisel P, Hennewig U, Blettner M, Spix C

      Abstract BACKGROUND: Radiotherapy is associated with a risk of subsequent neoplasms (SN) in childhood cancer survivors. It has been shown that children's thyroid glands are especially susceptible.

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    12. Skin Cancer Surveillance Behaviors Among Childhood Cancer Survivors

      The risk of developing skin cancer is elevated among childhood cancer survivors (CCS), particularly among those treated with radiation. This survey study examined the skin cancer surveillance behaviors of 94 CCS. Approximately 48% of CCS had ever conducted skin self-examination (SSE) and 31% had ever received a physician skin examination. Rates of physician skin examination were 2.5 times higher among CCS treated with radiation compared to those without radiation.

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      Mentions: Radiotherapy
    13. Psychosocial Late Effects in Pediatric Cancer Survivors: A Report From the Children's Oncology Group

      This review was conducted to update the Children's Oncology Group (COG) Long-Term Follow-Up Guidelines (COG-LTFU Guidelines, version 4.0) regarding screening for psychosocial late effects of pediatric cancer.

      Articles published between August 2009 and January 2011 that addressed psychosocial late effects of long-term survivors of pediatric cancer (n = 35) were reviewed by a multidisciplinary team of COG late effect experts.

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      Mentions: COG
    14. Standard of Care for Neuropsychological Monitoring in Pediatric Neuro-Oncology: Lessons From the Children's Oncology Group (COG).

      "We frame standards for neuropsychological monitoring of pediatric patients with CNS malignancy or who received cancer-directed therapies involving the CNS and discuss billing for these services in the United States in the context of clinical research. We describe a cost-effective, efficient model of neuropsychological monitoring that may increases access to neuropsychological care."

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      Mentions: Treatment COG
    15. Specialized survivor clinic attendance is associated with decreased rates of emergency department visits in adult survivors of childhood cancer.

      Specialized survivor clinic attendance is associated with decreased rates of emergency department visits in adult survivors of childhood cancer.

      Cancer. 2015 Sep 25;

      Authors: Sutradhar R, Agha M, Pole JD, Greenberg M, Guttmann A, Hodgson D, Nathan PC

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      Mentions: Side Effects
    16. Cardiac complications in childhood cancer survivors treated with anthracyclines.

      "Cardioprotective strategies during treatment are limited in children. Enalapril provides only temporary cardioprotection, whereas continuous anthracycline infusion extends none. On the other hand, dexrazoxane successfully prevents or reduces anthracycline-related cardiotoxicity in children with cancer, without increased risks for recurrence of primary or second malignancies or reductions in anti-tumour efficacy. With more childhood cancer survivors now reaching adulthood, it is vital to understand the adverse effects of cancer treatment on the cardiovascular system and their long-term consequences to identify and establish optimal prevention and management strategies that balance oncologic efficacy with long-term safety."

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      Mentions: Relapse
    17. Intestinal obstruction a long-term risk for survivors of childhood cancer

      Survivors of childhood cancer face a long-term risk for intestinal obstruction requiring surgery as a result of their treatment, according to findings from the Childhood Cancer Survivor Study.Late intestinal obstruction requiring surgery (IOS) appeared associated with an increased risk for mortality, making awareness of this condition even more important for survivors of childhood cancer, according to researchers.

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      Mentions: Side Effects
    1-24 of 80 1 2 3 4 »
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