1. Articles in category: Case Report

    1-24 of 82 1 2 3 4 »
    1. Thalidomide potentiates etoposide-induced apoptosis in murine neuroblastoma through suppression of NF-κB activation.

      Thalidomide potentiates etoposide-induced apoptosis in murine neuroblastoma through suppression of NF-κB activation.

      Pediatr Surg Int. 2018 Feb 08;:

      Authors: Hiramatsu T, Yoshizawa J, Miyaguni K, Sugihara T, Harada A, Kaji S, Uchida G, Kanamori D, Baba Y, Ashizuka S, Ohki T

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      Mentions: Treatment
    2. A highly malignant case of neuroblastoma with substantial increase of single-nucleotide variants and normal mismatch repair system: A case report.

      A highly malignant case of neuroblastoma with substantial increase of single-nucleotide variants and normal mismatch repair system: A case report.

      Medicine (Baltimore). 2017 Dec;96(50):e8845

      Authors: Yuan LQ, Wang JH, Zhu K, Yang M, Gu WZ, Lai C, Li HM, Shu Q, Chen X

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    3. Intravenous immunoglobulin with prednisone and risk-adapted chemotherapy for children with opsoclonus myoclonus ataxia syndrome associated with neuroblastoma (ANBL00P3): a randomised, open-label, phase 3 trial.

      Intravenous immunoglobulin with prednisone and risk-adapted chemotherapy for children with opsoclonus myoclonus ataxia syndrome associated with neuroblastoma (ANBL00P3): a randomised, open-label, phase 3 trial.

      Lancet Child Adolesc Health. 2018 Jan;2(1):25-34

      Authors: de Alarcon PA, Matthay KK, London WB, Naranjo A, Tenney SC, Panzer JA, Hogarty MD, Park JR, Maris JM, Cohn SL

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      Mentions: COG Chemotherapy
    4. Bioinformatics analysis of the CDK2 functions in neuroblastoma.

      Bioinformatics analysis of the CDK2 functions in neuroblastoma.

      Mol Med Rep. 2017 Dec 29;:

      Authors: Bo L, Wei B, Wang Z, Kong D, Gao Z, Miao Z

      Abstract The present study aimed to elucidate the potential mechanism of cyclin-dependent kinase 2 (CDK2) in neuroblastoma progression and to identify the candidate genes associated with neuroblastoma with CDK2 silencing. The microarray data of GSE16480 were obtained from the gene expression omnibus database.

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    5. Identification of the genetic and clinical characteristics of neuroblastomas using genome-wide analysis.

      Identification of the genetic and clinical characteristics of neuroblastomas using genome-wide analysis.

      Oncotarget. 2017 Dec 08;8(64):107513-107529

      Authors: Uryu K, Nishimura R, Kataoka K, Sato Y, Nakazawa A, Suzuki H, Yoshida K, Seki M, Hiwatari M, Isobe T, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Koh K, Hanada R, Oka A, Hayashi Y, Ohira M, Kamijo T, Nagase H, Takimoto T, Tajiri T, Nakagawara A, Ogawa S, Takita J

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      Mentions: ALK MYCN
    6. Coexpression network analysis identifies transcriptional modules associated with genomic alterations in neuroblastoma.

      Coexpression network analysis identifies transcriptional modules associated with genomic alterations in neuroblastoma.

      Biochim Biophys Acta. 2017 Dec 13;:

      Authors: Yang L, Li Y, Wei Z, Chang X

      Abstract Neuroblastoma is a highly complex and heterogeneous cancer in children. Acquired genomic alterations including MYCN amplification, 1p deletion and 11q deletion are important risk factors and biomarkers in neuroblastoma.

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      Mentions: MYCN Biomarkers
    7. MYCN Amplification Is Associated with Repressed Cellular Immunity in Neuroblastoma: An In Silico Immunological Analysis of TARGET Database.

      MYCN Amplification Is Associated with Repressed Cellular Immunity in Neuroblastoma: An In Silico Immunological Analysis of TARGET Database.

      Front Immunol. 2017;8:1473

      Authors: Zhang P, Wu X, Basu M, Dong C, Zheng P, Liu Y, Sandler AD

      Abstract Purpose: RNA and DNA sequencing data are traditionally used to discern intrinsic cellular pathways in cancer pathogenesis, their utility for investigating the tumor microenvironment (TME) has not been fully explored.

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      Mentions: MYCN
    8. Radical Surgery Improves Survival in Patients with Stage 4 Neuroblastoma.

      Radical Surgery Improves Survival in Patients with Stage 4 Neuroblastoma.

      World J Surg. 2017 Nov 10;:

      Authors: Vollmer K, Gfroerer S, Theilen TM, Bochennek K, Klingebiel T, Rolle U, Fiegel H

      Abstract BACKGROUND: Neuroblastoma (NBL) is the most common extracranial solid tumor in children. Despite a good overall prognosis in NBL patients, the outcome of children with stage 4 disease, even with multimodal intensive therapy, remains poor.

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      Mentions: Surgery
    9. Immunohistochemical analysis of PDK1, PHD3 and HIF-1α expression defines the hypoxic status of neuroblastoma tumors.

      Immunohistochemical analysis of PDK1, PHD3 and HIF-1α expression defines the hypoxic status of neuroblastoma tumors.

      PLoS One. 2017;12(11):e0187206

      Authors: Ognibene M, Cangelosi D, Morini M, Segalerba D, Bosco MC, Sementa AR, Eva A, Varesio L

      Abstract Neuroblastoma (NB) is the most common solid tumor during infancy and the first cause of death among the preschool age diseases.

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    10. MicroRNA profiles in neuroblastoma: Differences in risk and histology groups.

      MicroRNA profiles in neuroblastoma: Differences in risk and histology groups.

      Asia Pac J Clin Oncol. 2017 Nov 08;:

      Authors: Ergin K, Aktaş S, Altun Z, Dınız G, Olgun N

      Abstract AIM: To determine the miRNA expression profiles of neuroblastomas with different clinical and histological characteristics. METHODS: In this study 24 samples from 17 patients, paraffin blocks were used.

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    11. Comparison of diagnosing and staging accuracy of Pet (CT) and MIBG on patients with neuroblastoma: Systemic review and meta-analysis.

      Comparison of diagnosing and staging accuracy of PET (CT) and MIBG on patients with neuroblastoma: Systemic review and meta-analysis.

      J Huazhong Univ Sci Technolog Med Sci. 2017 Oct;37(5):649-660

      Authors: Xia J, Zhang H, Hu Q, Liu SY, Zhang LQ, Zhang A, Zhang XL, Wang YQ, Liu AG

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      Mentions: Staging MIBG
    12. Diagnosis of pediatric neuroblastoma by urine cytology: A case report.

      Diagnosis of pediatric neuroblastoma by urine cytology: A case report.

      Diagn Cytopathol. 2017 Oct 06;:

      Authors: Nishikawa S, Noguchi H, Tokumitsu T, Ohno A, Moriguchi-Goto S, Maekawa K, Asada Y, Moritake H, Kinoshita M, Yamada A, Takamura K, Sato Y

      Abstract Neuroblastomas are embryonal tumors arising from the neuronal crest cells of the synaptic nervous system. Findings from aspiration cytology have been reported, but there have been no reports of urine cytology findings.

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    13. Case report: value of gene expression profiling in the diagnosis of atypical neuroblastoma.

      Case report: value of gene expression profiling in the diagnosis of atypical neuroblastoma.

      BMC Res Notes. 2017 Aug 17;10(1):413

      Authors: Harttrampf AC, Chen Q, Jüttner E, Geiger J, Vansant G, Khan J, Kontny U

      Abstract BACKGROUND: Nephroblastoma and neuroblastoma belong to the most common abdominal malignancies in childhood.

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      Mentions: GPOH Imaging MYCN
    14. Individualized risk assessment in neuroblastoma: does the tumoral metabolic activity on (123)I-MIBG SPECT predict the outcome?

      Individualized risk assessment in neuroblastoma: does the tumoral metabolic activity on (123)I-MIBG SPECT predict the outcome?

      Eur J Nucl Med Mol Imaging. 2017 Aug 14;:

      Authors: Rogasch JMM, Hundsdoerfer P, Furth C, Wedel F, Hofheinz F, Krüger PC, Lode H, Brenner W, Eggert A, Amthauer H, Schatka I

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      Mentions: Imaging MYCN MIBG
    15. Elevated Preoperative Neutrophil-Lymphocyte Ratio is Predictive of a Poorer Prognosis for Pediatric Patients with Solid Tumors.

      Elevated Preoperative Neutrophil-Lymphocyte Ratio is Predictive of a Poorer Prognosis for Pediatric Patients with Solid Tumors.

      Ann Surg Oncol. 2017 Jul 17;:

      Authors: Nayak A, McDowell DT, Kellie SJ, Karpelowsky J

      Abstract BACKGROUND: An elevated neutrophil-lymphocyte ratio (NLR) has been shown to indicate poorer prognosis for adults with solid tumors and potentially represents an independent, universal adjunct prognostic factor.

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    16. Shallow whole genome sequencing on circulating cell-free DNA allows reliable non-invasive copy number profiling in neuroblastoma patients.

      Shallow whole genome sequencing on circulating cell-free DNA allows reliable non-invasive copy number profiling in neuroblastoma patients.

      Clin Cancer Res. 2017 Jul 14;:

      Authors: Van Roy N, Van der Linden M, Menten B, Dheedene A, Vandeputte C, Van Dorpe J, Laureys G, Renard M, Sante T, Lammens T, De Wilde B, Speleman F, De Preter K

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      Mentions: MYCN ATRX
    17. Altered erythropoiesis and decreased number of erythrocytes in children with neuroblastoma.

      Altered erythropoiesis and decreased number of erythrocytes in children with neuroblastoma.

      Oncotarget. 2017 May 30;:

      Authors: Morandi F, Barco S, Stigliani S, Croce M, Persico L, Lagazio C, Scuderi F, Belli ML, Montera M, Cangemi G, Pozzi S, Rigo V, Scaruffi P, Amoroso L, Erminio G, Pistoia V, Ferrini S, Corrias MV

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    18. Genomic analysis-integrated whole-exome sequencing of neuroblastomas identifies genetic mutations in axon guidance pathway.

      Genomic analysis-integrated whole-exome sequencing of neuroblastomas identifies genetic mutations in axon guidance pathway.

      Oncotarget. 2017 May 23;:

      Authors: Li Y, Ohira M, Zhou Y, Xiong T, Luo W, Yang C, Li X, Gao Z, Zhou R, Nakamura Y, Kamijo T, Kaneko Y, Taketani T, Ueyama J, Tajiri T, Zhang H, Wang J, Yang H, Yin Y, Nakagawara A

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      Mentions: ALK
    19. Chronic health conditions among long-term survivors of childhood cancer decrease over three decades as treatments improve

      Chronic health conditions among long-term survivors of childhood cancer decrease over three decades as treatments improve

      MEMPHIS, Tenn., June 2, 2017 /PRNewswire/ -- Changes in the treatment of pediatric cancer over recent decades have translated to a reduced risk of serious, long-term late health effects of cancer therapy. This is according to the latest analysis from the Childhood Cancer Survivor Study (CC...

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      Mentions: Treatment
    20. MYCN amplification predicts poor prognosis based on interphase fluorescence in situ hybridization analysis of bone marrow cells in bone marrow metastases of neuroblastoma.

      MYCN amplification predicts poor prognosis based on interphase fluorescence in situ hybridization analysis of bone marrow cells in bone marrow metastases of neuroblastoma.

      Cancer Cell Int. 2017;17:43

      Authors: Yue ZX, Huang C, Gao C, Xing TY, Liu SG, Li XJ, Zhao Q, Wang XS, Zhao W, Jin M, Ma XL

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      Mentions: MYCN Bone Marrow LDH
    21. Transcriptomic profiling of 39 commonly-used neuroblastoma cell lines.

      Transcriptomic profiling of 39 commonly-used neuroblastoma cell lines.

      Sci Data. 2017 Mar 28;4:170033

      Authors: Harenza JL, Diamond MA, Adams RN, Song MM, Davidson HL, Hart LS, Dent MH, Fortina P, Reynolds CP, Maris JM

      Abstract Neuroblastoma cell lines are an important and cost-effective model used to study oncogenic drivers of the disease.

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      Mentions: ALK MYCN
    22. Microarray expression analysis of MYCN-amplified neuroblastoma cells after inhibition of CDK2.

      Microarray expression analysis of MYCN-amplified neuroblastoma cells after inhibition of CDK2.

      Neoplasma. 2017 Mar 03;64(3):

      Authors: Song H, Wu F, Li S, Wang Z, Liu X, Cui Y, Lin C

      Abstract The study was aimed to explore the underlying molecular mechanisms of CDK2 inhibition in neuroblastoma by bioinformatics analysis. Gene expression profile GSE16480 was downloaded from the Gene Expression Omnibus.

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      Mentions: MYCN
    1-24 of 82 1 2 3 4 »
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