1. Articles in category: Funding

    1-24 of 54 1 2 3 »
    1. New Model for Predicting Neuroblastoma Outcomes Incorporates Early Developmental Signals

      Motivated by a desire to better understand the molecular circuitry underlying neuroblastoma and limitations of current methods for predicting disease progression and outcome, researchers from the Kulesa Lab at the Stowers Institute for Medical Research and collaborators at the University of Michigan and Oxford University set out to construct a logic-based model incorporating information about developmental signaling pathways implicated in the disease.

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      Mentions: ALK
    2. Network Modeling of microRNA-mRNA Interactions in Neuroblastoma Tumorigenesis Identifies miR-204 as a Direct Inhibitor of MYCN

      Network Modeling of microRNA-mRNA Interactions in Neuroblastoma Tumorigenesis Identifies miR-204 as a Direct Inhibitor of MYCN

      Neuroblastoma is a pediatric cancer of the sympathetic nervous system where MYCN amplification is a key indicator of poor prognosis. However, mechanisms by which MYCN promotes neuroblastoma tumorigenesis are not fully understood. In this study, we analyzed global miRNA and mRNA expression profiles of tissues at different stages of tumorigenesis from TH-MYCN transgenic mice, a model of MYCN-driven neuroblastoma.

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      Mentions: Imaging MYCN Genetics
    3. CureWorks Collaborative Launches to Accelerate Development of Immunotherapy Treatments for Childhood Cancers, Increase Access to Clinical Trials

      Seattle Children's, with participating members Children's National Health System, BC Children's Hospital and Children's Hospital Los Angeles, has launched CureWorks, an international collaborative of leading academic children's hospitals determined to accelerate the development of immunotherapy treatments for childhood cancer. CureWorks focuses on expanding immunotherapy trials and patient access around the world, as well as sharing data and collective expertise to advance novel cell therapies.

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      Mentions: Immunotherapy
    4. New study by MIT Sloan researchers provides insights on the challenges of developing drugs for pediatric cancer--and offers a potential solution

      New study by MIT Sloan researchers provides insights on the challenges of developing drugs for pediatric cancer--and offers a potential solution

      CAMBRIDGE, Mass., June 2, 2018 /PRNewswire-USNewswire/ -- Why is it so hard to develop drugs for children with cancer? And what can be done about it? Those questions are central to a new study published today in JAMA Oncology that explores new business models for funding drug...

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      Mentions: COG
    5. St. Jude Cloud, largest public repository of pediatric cancer genomics data, launches for researchers worldwide

      St. Jude Cloud, largest public repository of pediatric cancer genomics data, launches for researchers worldwide

      MEMPHIS, Tenn. and MOUNTAIN VIEW, Calif., April 12, 2018 /PRNewswire/ -- St. Jude Children's Research Hospital today launched St. Jude Cloud, an online data-sharing and collaboration platform that provides researchers access to the world's largest public repository of pediatric cancer...

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      Mentions: Genetics
    6. St. Jude Children's Research Hospital to develop $412 million advanced research center to propel discovery and scientific breakthroughs

      St. Jude Children's Research Hospital to develop $412 million advanced research center to propel discovery and scientific breakthroughs

      MEMPHIS, Tenn., Feb. 19, 2018 /PRNewswire-USNewswire/ -- A new era of scientific advancement is emerging at St. Jude Children's Research Hospital with the development of a $412-million advanced research center, the institution announced today. Designed as an interactive hub of...

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    7. 'Hijacker' drives cancer in some patients with high-risk neuroblastoma

      Researchers have identified mechanisms that drive about 10 percent of high-risk neuroblastoma cases and have used a new approach to show how the cancer genome “hijacks” DNA that regulates other genes. The resulting insights may help scientists develop more effective therapies, including ...

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    8. St. Baldrick's Foundation Appoints Neuroblastoma Expert, Dr. Susan Cohn, to its Board of Directors

      St. Baldrick's Foundation Appoints Neuroblastoma Expert, Dr. Susan Cohn, to its Board of Directors

      LOS ANGELES, Dec. 4, 2017 /PRNewswire-USNewswire/ -- The St. Baldrick's Foundation, the largest private funder of childhood cancer research grants, is proud to announce Dr. Susan Cohn, M.D., dean for Clinical Research at the University of Chicago Medicine & Biological Sciences, professor of pediatrics and section chief Hematology/Oncology in the Department of Pediatrics, as the newest member of its board of directors.

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    9. New study finds childhood cancer survivors commonly stay at jobs to keep health insurance

      New study finds childhood cancer survivors commonly stay at jobs to keep health insurance

      ( University of Utah Health ) The results of a national cancer survey find a significant number of childhood cancer survivors are worried about keeping their health insurance, to the point of letting it affect their career decisions. The findings were published today in JAMA Oncology.

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    10. NIH Funds Pediatric Data Resource Center.

      NIH Funds Pediatric Data Resource Center.

      Cancer Discov. 2017 Oct 11;:

      Authors:

      Abstract Children's Hospital of Philadelphia will lead a collaborative effort-funded with $14.8 million from the NIH-to pool genomic and phenotypic data from tens of thousands of patients to study the causes of pediatric cancer and structural birth defects.

      PMID: 29021134 [PubMed - as supplied by publisher]

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    11. Does Health Insurance Status Affect Childhood Cancer Survival?

      Does Health Insurance Status Affect Childhood Cancer Survival?

      Privately insured children and those with Medicaid at the time of a cancer diagnosis experience largely similar survival trends, with slight evidence for an increased risk of cancer death in children who were uninsured at diagnosis, finds a new study from the Brown School at Washington University in St. Louis.

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    12. Cell surface protein may offer big target in treating high-risk childhood cancers

      Cell surface protein may offer big target in treating high-risk childhood cancers

      ( Children's Hospital of Philadelphia ) Oncology researchers studying high-risk children's cancers have identified a protein that offers a likely target for immunotherapy -- harnessing the immune system in medical treatments. In cell cultures and animal models, a potent drug attached to an antibody selectively zeroes in on cancer cells without harming healthy cells.

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    13. Out-of-pocket health costs can cause financial problems for survivors of childhood cancer

      Out-of-pocket health costs can cause financial problems for survivors of childhood cancer

      Adult survivors of childhood cancer face an increased likelihood of financial difficulties related to out-of-pocket costs for their health care, compared with adults not affected by childhood cancer. In their report published online in the Journal of Clinical Oncology, investigators from the Massachusetts General Hospital (MGH) Cancer Center also report that survivors of childhood cancer who pay higher out-of-pocket costs were more than eight times more likely to have trouble paying their medical bills than were either survivors not facing higher out-of-pocket costs or adults without a history of childhood cancer.

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    14. RACE for Children Act Becomes Law!

      RACE for Children Act Becomes Law!

      WASHINGTON, Aug. 19, 2017 /PRNewswire/ -- Yesterday, the RACE for Children Act became law, ensuring that novel and exciting new cancer drugs will now be developed not only for adults, but also for children with cancer. Nancy Goodman, CEO of Kids v Cancer stated, "One of the greatest...

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    15. Kids First Data Resource Center set to ‘unlock potential’ of genomic data in pediatric cancer

      The NIH established the Kids First Data Resource Center, a pediatric cancer and rare disease data program that will enable clinicians and researchers to collaborate and access multiple genomic datasets.The resource center — the first of its kind in the pediatric research community — is designed to create a centralized, cloud-based database and discovery portal of clinical and genetic sequence data from various pediatric cancers and structural birth defects cohorts, such as congenital heart defects, hearing loss and cleft palate. The program also will develop analytical tools to provide access to this large-scale data for use in the discovery of novel ...

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      Mentions: Hearing Loss
    16. CHLA Researcher Awarded $1.9 Million by NIH to Study Novel Approach to Battling Neuroblastoma

      CHLA Researcher Awarded $1.9 Million by NIH to Study Novel Approach to Battling Neuroblastoma

      Muller Fabbri, MD, PhD, of the Children's Center for Cancer and Blood Diseases at Children's Hospital Los Angeles, has been awarded $1.9 million by the National Cancer Institute of the NIH to further his research on neuroblastoma.

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    17. Children's Hospital of Philadelphia to Lead New Pediatric Data Resource Center for Research in Childhood Cancer and Structural Birth Defects

      Children's Hospital of Philadelphia to Lead New Pediatric Data Resource Center for Research in Childhood Cancer and Structural Birth Defects

      PHILADELPHIA, Aug. 15, 2017 /PRNewswire-USNewswire/ -- The Center for Data Driven Discovery in Biomedicine at Children's Hospital of Philadelphia (CHOP) will lead a new, collaborative effort funded by the National Institutes of Health Common Fund to discover the causes of pediatric cancer...

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    18. New Tumor Database Deployed to Battle Childhood Cancer at UC Santa Cruz

      New Tumor Database Deployed to Battle Childhood Cancer at UC Santa Cruz

      The Treehouse Childhood Cancer Initiative researchers at UC Santa Cruz Genomics Institute and the St. Baldrick's Foundation are making a 11,000+ tumor database available for use by all researchers in the pediatric cancer community and beyond in our continued battle to take childhood back from cancer. The database contains RNA-Seq gene expression data, as well as age, disease, and sex.

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      Mentions: Genetics
    1-24 of 54 1 2 3 »
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