1. Articles in category: Children & Families

    1-24 of 99 1 2 3 4 5 »
    1. Parental perception of child vulnerability in childhood cancer survivors.

      Parental perception of child vulnerability in childhood cancer survivors.

      Pediatr Blood Cancer. 2018 Jul 19;:e27364

      Authors: Staba Hogan MJ, Ross WL, Balsamo L, Mitchell HR, Kadan-Lottick NS

      Abstract BACKGROUND: Parents' perception of their children's vulnerability to illness following cancer treatment is largely unknown, but is important to understand given known challenges of transitioning survivors to postcancer care.

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      Mentions: Treatment
    2. Clinical And Epidemiological Characteristics And Survival Outcomes Of Children With Neuroblastoma: 21 Years Of Experience At The Instituto De Oncologia PediÁtrica, In SÃo Paulo, Brazil.

      CLINICAL AND EPIDEMIOLOGICAL CHARACTERISTICS AND SURVIVAL OUTCOMES OF CHILDREN WITH NEUROBLASTOMA: 21 YEARS OF EXPERIENCE AT THE INSTITUTO DE ONCOLOGIA PEDIÁTRICA, IN SÃO PAULO, BRAZIL.

      Rev Paul Pediatr. 2018 Jul 10;:

      Authors: Lucena JN, Alves MTS, Abib SCV, Souza GO, Neves RPC, Caran EMM

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    3. Radioiodine (131I) therapies performed in a paediatric hospital: facilities and procedures.

      Radioiodine (131I) therapies performed in a paediatric hospital: facilities and procedures.

      Australas Phys Eng Sci Med. 2018 Jun 25;:

      Authors: Bibbo G, Benger T, Sigalas V, Kirkwood I

      Abstract Radioiodine (131I) therapies on younger children with thyroid cancer and neuroblastoma can be challenging as they are required to be isolated for a period of time due to radiation safety concerns. At our hospital these therapies are performed in a purpose-built child-friendly therapy room.

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    4. Network Modeling of microRNA-mRNA Interactions in Neuroblastoma Tumorigenesis Identifies miR-204 as a Direct Inhibitor of MYCN

      Network Modeling of microRNA-mRNA Interactions in Neuroblastoma Tumorigenesis Identifies miR-204 as a Direct Inhibitor of MYCN

      Neuroblastoma is a pediatric cancer of the sympathetic nervous system where MYCN amplification is a key indicator of poor prognosis. However, mechanisms by which MYCN promotes neuroblastoma tumorigenesis are not fully understood. In this study, we analyzed global miRNA and mRNA expression profiles of tissues at different stages of tumorigenesis from TH-MYCN transgenic mice, a model of MYCN-driven neuroblastoma.

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      Mentions: Imaging MYCN Genetics
    5. CureWorks Collaborative Launches to Accelerate Development of Immunotherapy Treatments for Childhood Cancers, Increase Access to Clinical Trials

      Seattle Children's, with participating members Children's National Health System, BC Children's Hospital and Children's Hospital Los Angeles, has launched CureWorks, an international collaborative of leading academic children's hospitals determined to accelerate the development of immunotherapy treatments for childhood cancer. CureWorks focuses on expanding immunotherapy trials and patient access around the world, as well as sharing data and collective expertise to advance novel cell therapies.

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      Mentions: Immunotherapy
    6. Comparison of long-term prognosis of laparoscopic and open adrenalectomy for local adrenal neuroblastoma in children.

      Comparison of long-term prognosis of laparoscopic and open adrenalectomy for local adrenal neuroblastoma in children.

      Pediatr Surg Int. 2018 Jun 07;:

      Authors: Yao W, Dong K, Li K, Zheng S, Xiao X

      Abstract OBJECTIVE: To investigate and compare long-term outcomes in children undergoing laparoscopic or open adrenalectomy for local adrenal neuroblastoma.

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    7. Rigorous study finds widely used treatment for infection fails young cancer patients

      Rigorous study finds widely used treatment for infection fails young cancer patients

      ( St. Jude Children's Research Hospital ) St. Jude Children's Research Hospital found ethanol-lock therapy failed to prevent new or recurring infections in cancer patients with central venous catheters and was associated with increased complications.

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      Mentions: Treatment
    8. Investigating the Microbiome and Volatilome of Children With Neuroblastoma

      Investigating the Microbiome and Volatilome of Children With Neuroblastoma

      Conditions :   Microbial Colonization;   Neuroblastoma;   Children, Only Interventions :   Diagnostic Test: Initial fecal microbiome;   Diagnostic Test: Initial fecal volatile organic compounds;   Diagnostic Test: Initial breath volatile organic compounds;   Diagnostic Test: Microbiome under chemotherapy;   Diagnostic Test: Fecal volatile organic compounds under chemotherapy;   Diagnostic Test: Breath volatile organic compounds under chemotherapy;   Diagnostic Test: Final microbiome;   Diagnostic Test: Final fecal volatile organic compounds;   Diagnostic Test: Final breath volatile organic compounds Sponsor :   Medical University of Graz Recruiting

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      Mentions: Chemotherapy
    9. Childhood Cancer Facts: By the Numbers

      Childhood Cancer Facts: By the Numbers

      Every year, an estimated 250,000+ new cases of cancer affect children under the age of 20 worldwide. Despite this, childhood cancer research is vastly and consistently underfunded. Check out the infographic below for more childhood cancer facts. You can also view and download the kid-friendly "Did You Know? Childhood Cancer Facts For Kids" infographic.

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    10. miRNA expression profile of bone marrow resident cells from children with neuroblastoma is not significantly different from that of healthy children.

      miRNA expression profile of bone marrow resident cells from children with neuroblastoma is not significantly different from that of healthy children.

      Oncotarget. 2018 Apr 10;9(27):19014-19025

      Authors: Stigliani S, Morandi F, Persico L, Lagazio C, Erminio G, Scaruffi P, Corrias MV

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      Mentions: Bone Marrow
    11. Romiplostim for Immune Thrombocytopenia in Neuroblastoma Patients Receiving Chemotherapy.

      Romiplostim for Immune Thrombocytopenia in Neuroblastoma Patients Receiving Chemotherapy.

      J Pediatr Hematol Oncol. 2018 Apr 20;:

      Authors: Fassel H, Bussel JB, Roberts SS, Modak S

      Abstract Thrombocytopenia, a serious complication of myelosuppressive chemotherapy in cancer patients, is managed with platelet transfusions until recovery of platelet counts. However, children receiving chemotherapy can rarely develop immune thrombocytopenia (ITP) that is refractory to transfused platelets.

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    12. [Clinical features and prognosis of malignancy-associated hemophagocytic lymphohistiocytosis in children: a clinical analysis of 24 cases].

      [Clinical features and prognosis of malignancy-associated hemophagocytic lymphohistiocytosis in children: a clinical analysis of 24 cases].

      Zhongguo Dang Dai Er Ke Za Zhi. 2018 Apr;20(4):295-297

      Authors: Zhang WY, Zhang Y, Dong NN, Wang YC, Sheng GY, Xu XJ, Liu YF

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    13. Parent understanding of the risk of future limitations secondary to pediatric cancer treatment

      Parents and physicians may have different understandings of a child's risk of future limitations due to cancer or cancer treatment. We evaluated alignment between parent‐ and physician‐estimated risk of late effects. We surveyed 352 parents of children with cancer within 12 weeks of diagnosis, and the children's oncologists, at Dana‐Farber/Boston Children's Cancer and Blood Disorders Center and Children's Hospital of Philadelphia.

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      Mentions: Treatment
    14. A molecular map of childhood cancers

      A molecular map of childhood cancers

      Researchers led by Professor Stefan Pfister from the “Hopp Children’s Cancer Center at the NCT Heidelberg” (KiTZ) have been able to draw an extremely detailed molecular map of childhood cancers. In close collaboration with the German Cancer Consortium (DKTK) and the Society for Pediatric Oncology and Hematology (GPOH), they screened almost 1,000 tumor samples from […]

      The post A molecular map of childhood cancers appeared first on Healthcanal.com.

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      Mentions: GPOH Genetics
    15. Association between NEFL Gene Polymorphisms and Neuroblastoma Risk in Chinese Children: A Two-Center Case-Control Study.

      Association between NEFL Gene Polymorphisms and Neuroblastoma Risk in Chinese Children: A Two-Center Case-Control Study.

      J Cancer. 2018;9(3):535-539

      Authors: Wu Q, Zhuo ZJ, Zeng J, Zhang J, Zhu J, Zou Y, Zhang R, Yang T, Zhu D, He J, Xia H

      Abstract Neuroblastoma is a lethal tumor that mainly occurs in children. To date, the genetic etiology of sporadic neuroblastoma remains obscure.

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    16. St. Jude Children's Research Hospital to develop $412 million advanced research center to propel discovery and scientific breakthroughs

      St. Jude Children's Research Hospital to develop $412 million advanced research center to propel discovery and scientific breakthroughs

      MEMPHIS, Tenn., Feb. 19, 2018 /PRNewswire-USNewswire/ -- A new era of scientific advancement is emerging at St. Jude Children's Research Hospital with the development of a $412-million advanced research center, the institution announced today. Designed as an interactive hub of...

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    17. Delay in reforming European rules could deny thousands of children access to latest cancer drugs

      Thousands of children with cancer across Europe could miss out on the latest targeted treatments because of delays reforming outdated regulations, leading cancer research institutions, charities and expert bodies are warning.

      The European Commission has...

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    18. Delay in reforming European rules could deny thousands of children access to latest cancer drugs

      Delay in reforming European rules could deny thousands of children access to latest cancer drugs

      Thousands of children with cancer across Europe could miss out on the latest targeted treatments because of delays reforming outdated regulations, leading cancer research institutions, charities and expert bodies are warning.

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    19. Change in liver, spleen and bone marrow magnetic resonance imaging signal intensity over time in children with solid abdominal tumors.

      Change in liver, spleen and bone marrow magnetic resonance imaging signal intensity over time in children with solid abdominal tumors.

      Pediatr Radiol. 2017 Dec 19;:

      Authors: Sirignano M, Dillman JR, Weiss BD, Quinn CT, Zhang B, Su W, Trout AT

      Abstract BACKGROUND: Reticuloendothelial system MRI signal hypointensity is common in pediatric oncology patients with solid abdominal tumors.

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      Mentions: Imaging Bone Marrow
    20. Immune Thrombocytopenia in a Child with Neuroblastoma.

      Immune Thrombocytopenia in a Child with Neuroblastoma.

      Case Rep Pediatr. 2017;2017:1329489

      Authors: Ikizoglu HT, Ayan I, Tokat F, Tecimer T, Topuzlu Tekant G

      Abstract Thrombocytopenia is a frequent finding in patients with solid tumors. It is usually caused by bone marrow infiltration or by myelosuppression due to anticancer therapy; however immune thrombocytopenia (ITP) associated with solid tumors is rare. Neuroblastoma is the most common extracranial solid tumor in children.

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      Mentions: Bone Marrow
    21. NIH Funds Pediatric Data Resource Center.

      NIH Funds Pediatric Data Resource Center.

      Cancer Discov. 2017 Oct 11;:

      Authors:

      Abstract Children's Hospital of Philadelphia will lead a collaborative effort-funded with $14.8 million from the NIH-to pool genomic and phenotypic data from tens of thousands of patients to study the causes of pediatric cancer and structural birth defects.

      PMID: 29021134 [PubMed - as supplied by publisher]

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    1-24 of 99 1 2 3 4 5 »
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