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Genome-wide analysis of HOXC9-induced neuronal differentiation of neuroblastoma cells.
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TrkAIII signals endoplasmic reticulum stress to the mitochondria in neuroblastoma cells, resulting in glycolytic metabolic adaptation.

ncbi.nlm.nih.gov

TrkAIII signals endoplasmic reticulum stress to the mitochondria in neuroblastoma cells, resulting in glycolytic metabolic adaptation.

Oncotarget. 2018 Feb 02;9(9):8368-8390

Authors: Farina AR, Cappabianca L, Gneo L, Ruggeri P, Mackay AR

Abstract Alternative TrkAIII splicing characterises advanced stage metastatic disease and post-therapeutic relapse in neuroblastoma (NB), and in NB models TrkAIII exhibits oncogenic activity.

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