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Utility of Phox2b Immunohistochemical Stain in Neural Crest Tumors and Non-neural Crest Tumors in Pediatric Patients.

ncbi.nlm.nih.gov

Utility of Phox2b Immunohistochemical Stain in Neural Crest Tumors and Non-neural Crest Tumors in Pediatric Patients.

Histopathology. 2017 Oct 07;:

Authors: Warren M, Matsuno R, Tran H, Shimada H

Abstract BACKGROUND: This study evaluated the utility of Phox2b in pediatric tumors. Previously tyrosine hydroxylase (TH) was the most widely utilized sympathoadrenal marker specific for neural crest tumors with neuronal/neuroendocrine differentiation. However, its sensitivity is insufficient.

Mentions: PHOX2B