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Immunological Resolution of Human Chronic Graft-versus-Host Disease.
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When LMO1 Meets MYCN, Neuroblastoma Is Metastatic.

ncbi.nlm.nih.gov

When LMO1 Meets MYCN, Neuroblastoma Is Metastatic.

Cancer Cell. 2017 Sep 11;32(3):273-275

Authors: Liu Z, Thiele CJ

Abstract LMO1 is a high-risk neuroblastoma susceptibility gene, but how LMO1 cooperates with MYCN in neuroblastoma tumorigenesis is unclear. In this issue of Cancer Cell, Zhu et al. develop a novel zebrafish model that elucidates a mechanism by which LMO1 and MYCN synergistically initiate neuroblastoma and contribute to metastatic disease progression.

Mentions: MYCN Tumorigenesis