1. Nanoparticles give immune cells a boost

    Nanoparticles give immune cells a boost

    ( Massachusetts Institute of Technology ) MIT researchers have devised a novel way to boost the effectiveness of T cell therapy against solid tumors. By attaching nanoparticle 'backpacks' carrying immune-stimulating drugs directly to T cells, the MIT engineers showed that they could enhance those T cells' response without inducing harmful side effects.

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  2. Quotes

    1. We found you could greatly improve the efficacy of the T cell therapy with backpacked drugs that help the donor T cells survive and function more effectively. Even more importantly, we achieved that without any of the toxicity that you see with systemic injection of the drugs.
    2. The general idea is to grow up large numbers of T cells that are tumor specific and then infuse them in patients.
    3. That allowed us to link T cell activation to the drug release rate.
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