1. S-trityl-L-cysteine, a novel Eg5 inhibitor, is a potent chemotherapeutic strategy in neuroblastoma.

    S-trityl-L-cysteine, a novel Eg5 inhibitor, is a potent chemotherapeutic strategy in neuroblastoma.

    Oncol Lett. 2018 Jul;16(1):1023-1030

    Authors: Wu W, Jingbo S, Xu W, Liu J, Huang Y, Sheng Q, Lv Z

    Abstract Eg5 is a member of the kinesin-5 family. It is involved in the formation of the bipolar spindle and serves a crucial role in mitosis; meaning that mitotic activation may serve as a chemotherapeutic strategy.

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