1. A molecular map of childhood cancers

    A molecular map of childhood cancers

    Researchers led by Professor Stefan Pfister from the “Hopp Children’s Cancer Center at the NCT Heidelberg” (KiTZ) have been able to draw an extremely detailed molecular map of childhood cancers. In close collaboration with the German Cancer Consortium (DKTK) and the Society for Pediatric Oncology and Hematology (GPOH), they screened almost 1,000 tumor samples from […]

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    1. It turned out in about half of the patients that genetic alterations affected cancer cells so that they are potential targets for so-called targeted anticancer drugs.
    2. Most of these drugs have not yet been tested for children. It remains to be seen whether they are also safe and effective in young patients.
    3. Compared to tumors in adults, the investigations revealed large variations in the type and incidence of mutated genes.
    4. This confirms once more that tumor development proceeds in fundamentally different ways in children compared to adults.
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