Legumain correlates with neuroblastoma differentiation and can be used in prodrug design.
Chem Biol Drug Des. 2017 Oct 10;:
Authors: Zhang M, Jiang Z, Chen S, Wu Z, Chen K, Wu Y
Abstract Neuroblastoma (NB) is a highly malignant solid tumor in children. The cysteine endopeptidase legumain is expressed in adult solid tumors, but its expression in NB has not been examined.