1. Researchers identify gene variants linked to a high-risk children's cancer

    Researchers identify gene variants linked to a high-risk children's cancer

    ( Children's Hospital of Philadelphia ) Pediatric researchers investigating the childhood cancer neuroblastoma have identified common gene variants that raise the risk of an aggressive form of that disease. The discovery may assist doctors in better diagnosing subtypes of neuroblastoma.

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  2. Quotes

    1. These inherited variants predispose to 11q deletions, which are a strong risk factor for an aggressive form of neuroblastoma.
    2. We already knew that 11q deletions are biomarkers that predict poor outcomes in neuroblastoma.
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