1. Possible New Combination Treatment for Cancer

    A few years ago, a molecule known as "JQ1" was developed, which can block so called BET bromodomain proteins. This switch off the known cancer gene MYC thereby preventing cancer cells from dividing. The discovery was regarded as a major breakthrough. A problem was that JQ1 did not function optimally in animal experiments, and this means that it has not been possible to test the treatment on cancer patients. New molecule

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    1. We hypothesized that the new molecule could also switch off the MYC gene. However, our studies show that neither the JQ1 molecule nor the RVX2135 molecule have this property in these types of cells. This means that the mode of action is probably not as simple as we believed.