1. A Phase I Study of Humanized 3F8 plus Interleukin-2 in Patients with High-Risk Neuroblastoma and GD2-Positive Tumors

    Memorial Sloan Kettering Cancer Center Clinical Research

    Protocol
    12-116

    Full Title
    Phase I Study of Humanized 3F8 Monoclonal Antibody (Hu3F8) when Combined with Interleukin-2 in Patients With High-Risk Neuroblastoma and GD2-positive Solid Tumors

    Phase
    I

    Disease Status
    Relapsed/Refractory

    Purpose

    3F8 is an antibody that attaches to neuroblastoma cells and helps focus a patient’s own immune system - especially white blood cells - to attack neuroblastoma cells. Conventional 3F8 is made from mouse cells.

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