SAHA sensitizes neuroblastoma to paclitaxel by inhibiting TRP14-mediated autophagy.
Cancer Sci. 2017 May 12;:
Authors: Zhen Z, Yang K, Ye L, You Z, Chen R, Liu Y, He Y
Abstract Paclitaxel is not as effective for neuroblastoma as most of the front-line chemotherapeutics due to drug resistance. This study explored the regulatory mechanism of paclitaxel-associated autophagy and potential solutions to paclitaxel resistance in neuroblastoma.