1. Success of sensory cell regeneration raises hope for hearing restoration

    Success of sensory cell regeneration raises hope for hearing restoration

    Scientists have regenerated immature auditory hair cells in adult mice by manipulating two genes, suggesting that the research offers clues for better treatment of hearing loss.

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  2. Quotes

    1. In this study, we looked to Mother Nature for answers and we were rewarded.
    2. Work in other organs has shown that reprogramming cells is rarely accomplished by manipulating a single factor.
    3. This study suggests that targeting p27, GATA3 and POU4F3 may enhance the outcome of gene therapy and other approaches that aim to restart ATOH1 expression.
    4. Work continues to identify the other factors, including small molecules, necessary to not only promote the maturation and survival of the newly generated hair cells, but also increase their number.
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