1. Experimental antibody temporarily halts progression of neuroblastoma in children

    Tumors shrank or disappeared and disease progression was temporarily halted in 15 children with advanced neuroblastoma enrolled in a safety study of an experimental Antibody-What-is-an-Antibody.aspx">antibody produced at St. Jude Children's Research Hospital. Four patients are still alive after more than two-and-a-half years and without additional treatment.

    Findings from the Phase I study were published recently online and will appear in the May 10 edition of the Journal of Clinical Oncology. The results prompted St. Jude to expand clinical trials of the monoclonal antibody hu14.18K322A to include patients newly diagnosed with neuroblastoma. Monoclonal antibodies are ...

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    1. This was the first time this experimental antibody was tried in patients. We were encouraged with the response.
    2. Four patients are alive after more than two-and-a-half years without additional therapy.
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