1. Significance of tumor biology compared to metastatic pattern (INSS 4 versus 4s) and age for prognosis of neuroblastoma less than 18 months of age.

    "For patients with MYCN not amplified tumors, outcome for patients 12-18 months is similar to those <12 months regardless of the pattern of metastases. Tumor biology is more critical than metastatic pattern for prognosis of patients aged 12-18 months with stage 4 neuroblastoma."

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