1. Histone deacetylase 6 inhibition enhances oncolytic viral therapy

    Histone deacetylase 6 inhibition enhances oncolytic viral therapy

    Gliomas are extremely aggressive brain tumors that are resistant to standard cancer therapeutics. Oncolytic viral (OV) therapy, which uses engineered viruses to infect and target tumor cells for destruction by the immune system, is currently being explored for use in refractory cancers.

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