1. Pinpointing Mutations in a Relapsed Cancer May Lead to Better Treatments

    Researchers studying the pediatric cancer neuroblastoma have detailed how cancer-driving mutations evolve during chemotherapy, and they hope to exploit this knowledge to design better treatments for children.

    “Our greater understanding of mutations on a crucial biological pathway offers prospects of acting on these pathways for direct benefit to children with this aggressive form of neuroblastoma,” said senior author John M. Maris, MD, a pediatric oncologistat The Children’s Hospital of Philadelphia.

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