Chimeric antigen receptors and bispecific antibodies to retarget T cells in pediatric oncology.
Pediatr Blood Cancer. 2015 Apr 1;
Authors: Suzuki M, Curran KJ, Cheung NK
Abstract Cancer immunotherapy using antigen-specific T cells has broad therapeutic potential. Chimeric antigen receptors and bispecific antibodies can redirect T cells to kill tumors without human leukocyte antigens (HLA) restriction.